BRD-K68246049_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

60 genes differentially expressed following the BRD-K68246049_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
AUTS2 autism susceptibility candidate 2
BHLHE41 basic helix-loop-helix family, member e41
CCL5 chemokine (C-C motif) ligand 5
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CPD carboxypeptidase D
CTSS cathepsin S
CXCL8 chemokine (C-X-C motif) ligand 8
CYBA cytochrome b-245, alpha polypeptide
DHRS3 dehydrogenase/reductase (SDR family) member 3
HOXA4 homeobox A4
HOXA5 homeobox A5
IGFBP3 insulin-like growth factor binding protein 3
LAMA3 laminin, alpha 3
LIMCH1 LIM and calponin homology domains 1
LOX lysyl oxidase
NAMPT nicotinamide phosphoribosyltransferase
PDZK1IP1 PDZK1 interacting protein 1
PLBD1 phospholipase B domain containing 1
PSAT1 phosphoserine aminotransferase 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
SDC4 syndecan 4
SKAP2 src kinase associated phosphoprotein 2
STAR steroidogenic acute regulatory protein
TLR4 toll-like receptor 4
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TRIM2 tripartite motif containing 2
TSC22D3 TSC22 domain family, member 3
TSKU tsukushi, small leucine rich proteoglycan
TUBB2B tubulin, beta 2B class IIb
TXNIP thioredoxin interacting protein
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
BAG3 BCL2-associated athanogene 3
CCL19 chemokine (C-C motif) ligand 19
CCND1 cyclin D1
CCND2 cyclin D2
COL4A6 collagen, type IV, alpha 6
CORO1C coronin, actin binding protein, 1C
ESR1 estrogen receptor 1
GRB14 growth factor receptor-bound protein 14
H2BFS H2B histone family, member S (pseudogene)
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
LGALS1 lectin, galactoside-binding, soluble, 1
MFAP5 microfibrillar associated protein 5
NELL2 NEL-like 2 (chicken)
ODC1 ornithine decarboxylase 1
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
PTGDS prostaglandin D2 synthase 21kDa (brain)
RTN1 reticulon 1
SCGB1D2 secretoglobin, family 1D, member 2
SLC6A15 solute carrier family 6 (neutral amino acid transporter), member 15
SMTN smoothelin
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12)
SPDEF SAM pointed domain containing ETS transcription factor
TSPAN4 tetraspanin 4
TUBA1A tubulin, alpha 1a