BRD-K68191783_ALW-II-38-3_PC3_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

73 genes differentially expressed following the BRD-K68191783_ALW-II-38-3_PC3_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGTR1 angiotensin II receptor, type 1
BMP7 bone morphogenetic protein 7
CLEC11A C-type lectin domain family 11, member A
COBL cordon-bleu WH2 repeat protein
CXCL2 chemokine (C-X-C motif) ligand 2
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FOLR1 folate receptor 1 (adult)
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
HBB hemoglobin, beta
IGF1R insulin-like growth factor 1 receptor
KDM5D lysine (K)-specific demethylase 5D
LCN2 lipocalin 2
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MMP12 matrix metallopeptidase 12
MMP9 matrix metallopeptidase 9
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
TEX10 testis expressed 10
TJP2 tight junction protein 2
VAV3 vav 3 guanine nucleotide exchange factor

decreased expression

Symbol Name
ADM adrenomedullin
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALCAM activated leukocyte cell adhesion molecule
ANXA1 annexin A1
APOD apolipoprotein D
ARG2 arginase 2
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CD163 CD163 molecule
CD36 CD36 molecule (thrombospondin receptor)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CFB complement factor B
CPE carboxypeptidase E
CRABP2 cellular retinoic acid binding protein 2
CXCL14 chemokine (C-X-C motif) ligand 14
EPAS1 endothelial PAS domain protein 1
EVI2A ecotropic viral integration site 2A
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
GPX3 glutathione peroxidase 3
HSPA1A heat shock 70kDa protein 1A
IFI44 interferon-induced protein 44
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGFBP5 insulin-like growth factor binding protein 5
IGL immunoglobulin lambda locus
IPO13 importin 13
JCHAIN joining chain of multimeric IgA and IgM
NFIB nuclear factor I/B
NT5E 5'-nucleotidase, ecto (CD73)
PCOLCE2 procollagen C-endopeptidase enhancer 2
PIP prolactin-induced protein
PLIN2 perilipin 2
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RGS5 regulator of G-protein signaling 5
RHOB ras homolog family member B
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCGB2A2 secretoglobin, family 2A, member 2
SDC1 syndecan 1
SHB Src homology 2 domain containing adaptor protein B
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SOX9 SRY (sex determining region Y)-box 9
STXBP2 syntaxin binding protein 2
TM9SF3 transmembrane 9 superfamily member 3
TMEM45A transmembrane protein 45A
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TXNDC9 thioredoxin domain containing 9
XIST X inactive specific transcript (non-protein coding)
ZNF395 zinc finger protein 395