BRD-K68174511_torin-2_MCF7_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

150 genes differentially expressed following the BRD-K68174511_torin-2_MCF7_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACAA2 acetyl-CoA acyltransferase 2
ADD3 adducin 3 (gamma)
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKR1C2 aldo-keto reductase family 1, member C2
AMIGO2 adhesion molecule with Ig-like domain 2
AREG amphiregulin
ARID4B AT rich interactive domain 4B (RBP1-like)
BAZ2B bromodomain adjacent to zinc finger domain, 2B
C10ORF10 chromosome 10 open reading frame 10
C3 complement component 3
C8ORF4 chromosome 8 open reading frame 4
CBR3 carbonyl reductase 3
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
COL10A1 collagen, type X, alpha 1
CP ceruloplasmin (ferroxidase)
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CXCR4 chemokine (C-X-C motif) receptor 4
CYBA cytochrome b-245, alpha polypeptide
DHRS3 dehydrogenase/reductase (SDR family) member 3
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
EGFR epidermal growth factor receptor
EIF5A eukaryotic translation initiation factor 5A
EMX2 empty spiracles homeobox 2
EPN2 epsin 2
FAM13A family with sequence similarity 13, member A
FGB fibrinogen beta chain
FGG fibrinogen gamma chain
FKBP14 FK506 binding protein 14, 22 kDa
FXYD5 FXYD domain containing ion transport regulator 5
GADD45B growth arrest and DNA-damage-inducible, beta
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GPRC5A G protein-coupled receptor, class C, group 5, member A
GSTM1 glutathione S-transferase mu 1
GSTM2 glutathione S-transferase mu 2 (muscle)
GUSBP11 glucuronidase, beta pseudogene 11
HBP1 HMG-box transcription factor 1
HIST1H1C histone cluster 1, H1c
HIST1H2BD histone cluster 1, H2bd
HIST1H2BG histone cluster 1, H2bg
IGHM immunoglobulin heavy constant mu
IGL immunoglobulin lambda locus
IL7R interleukin 7 receptor
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
JUP junction plakoglobin
KIAA0226L KIAA0226-like
KIF20A kinesin family member 20A
KLF6 Kruppel-like factor 6
KRT7 keratin 7, type II
LDOC1 leucine zipper, down-regulated in cancer 1
LIMCH1 LIM and calponin homology domains 1
LOC100272216 uncharacterized LOC100272216
LY86 lymphocyte antigen 86
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAL mal, T-cell differentiation protein
MDFIC MyoD family inhibitor domain containing
METTL7A methyltransferase like 7A
MTUS1 microtubule associated tumor suppressor 1
MVP major vault protein
NNMT nicotinamide N-methyltransferase
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PAN2 PAN2 poly(A) specific ribonuclease subunit
PDZK1IP1 PDZK1 interacting protein 1
PLA2G16 phospholipase A2, group XVI
PLK1 polo-like kinase 1
PNKP polynucleotide kinase 3'-phosphatase
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
RAB11FIP2 RAB11 family interacting protein 2 (class I)
RAP1GAP RAP1 GTPase activating protein
RHOBTB3 Rho-related BTB domain containing 3
SAT1 spermidine/spermine N1-acetyltransferase 1
SOCS2 suppressor of cytokine signaling 2
SPP1 secreted phosphoprotein 1
STX1A syntaxin 1A (brain)
TBC1D31 TBC1 domain family, member 31
TOP2A topoisomerase (DNA) II alpha 170kDa
TSPAN5 tetraspanin 5
VAMP8 vesicle-associated membrane protein 8
VLDLR very low density lipoprotein receptor
XIST X inactive specific transcript (non-protein coding)
ZBTB20 zinc finger and BTB domain containing 20
ZHX2 zinc fingers and homeoboxes 2

decreased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ADO 2-aminoethanethiol (cysteamine) dioxygenase
AQP3 aquaporin 3 (Gill blood group)
ATF5 activating transcription factor 5
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CALML4 calmodulin-like 4
CANT1 calcium activated nucleotidase 1
CAPRIN1 cell cycle associated protein 1
CCND1 cyclin D1
CCND2 cyclin D2
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CHGB chromogranin B
CPE carboxypeptidase E
CST7 cystatin F (leukocystatin)
CXCL14 chemokine (C-X-C motif) ligand 14
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DMD dystrophin
DUSP2 dual specificity phosphatase 2
EFHD1 EF-hand domain family, member D1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM57A family with sequence similarity 57, member A
FERMT1 fermitin family member 1
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
FXYD3 FXYD domain containing ion transport regulator 3
GATA2 GATA binding protein 2
GCH1 GTP cyclohydrolase 1
GJA1 gap junction protein, alpha 1, 43kDa
HBB hemoglobin, beta
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12
ITM2A integral membrane protein 2A
JAG1 jagged 1
KIAA0125 KIAA0125
KLF5 Kruppel-like factor 5 (intestinal)
KRT5 keratin 5, type II
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAT2A methionine adenosyltransferase II, alpha
MIR22HG MIR22 host gene
MYBPC1 myosin binding protein C, slow type
OLFM1 olfactomedin 1
PI3 peptidase inhibitor 3, skin-derived
PODXL podocalyxin-like
PRKRIR protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
RALGDS ral guanine nucleotide dissociation stimulator
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SAMD4A sterile alpha motif domain containing 4A
SCG2 secretogranin II
SEPP1 selenoprotein P, plasma, 1
SFN stratifin
SLC25A46 solute carrier family 25, member 46
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SNAI2 snail family zinc finger 2
SNAP25 synaptosomal-associated protein, 25kDa
SPRR1A small proline-rich protein 1A
STAB1 stabilin 1
SUB1 SUB1 homolog (S. cerevisiae)
TMEM70 transmembrane protein 70
TSPAN8 tetraspanin 8
WSB2 WD repeat and SOCS box containing 2
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta