BRD-K68174511_torin-2_BT20_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

39 genes differentially expressed following the BRD-K68174511_torin-2_BT20_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
ADAM10 ADAM metallopeptidase domain 10
ADGRG6 adhesion G protein-coupled receptor G6
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
CCNG2 cyclin G2
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHIC2 cysteine-rich hydrophobic domain 2
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CRYAB crystallin, alpha B
CX3CR1 chemokine (C-X3-C motif) receptor 1
EGR1 early growth response 1
EPCAM epithelial cell adhesion molecule
ERBB3 erb-b2 receptor tyrosine kinase 3
GBP2 guanylate binding protein 2, interferon-inducible
GLUL glutamate-ammonia ligase
HBP1 HMG-box transcription factor 1
IGHM immunoglobulin heavy constant mu
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL7R interleukin 7 receptor
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT19 keratin 19, type I
LEF1 lymphoid enhancer-binding factor 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
NID2 nidogen 2 (osteonidogen)
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
TGFBR3 transforming growth factor, beta receptor III
VAV3 vav 3 guanine nucleotide exchange factor
VCAN versican
VSNL1 visinin-like 1

decreased expression

Symbol Name
CCND1 cyclin D1
CD24 CD24 molecule
EFNB2 ephrin-B2
HPCAL1 hippocalcin-like 1
PNP purine nucleoside phosphorylase
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1