BRD-K68143200_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

74 genes differentially expressed following the BRD-K68143200_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABHD4 abhydrolase domain containing 4
ABLIM1 actin binding LIM protein 1
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
AREG amphiregulin
CBR3 carbonyl reductase 3
CXCL13 chemokine (C-X-C motif) ligand 13
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DUSP1 dual specificity phosphatase 1
EMP1 epithelial membrane protein 1
FABP7 fatty acid binding protein 7, brain
FGFR3 fibroblast growth factor receptor 3
FOSL1 FOS-like antigen 1
G6PD glucose-6-phosphate dehydrogenase
GCLM glutamate-cysteine ligase, modifier subunit
GPX2 glutathione peroxidase 2
GRB7 growth factor receptor-bound protein 7
H2BFS H2B histone family, member S (pseudogene)
HMOX1 heme oxygenase 1
HOXB7 homeobox B7
HSPG2 heparan sulfate proteoglycan 2
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
JAG1 jagged 1
KIAA1598
KRT6B keratin 6B, type II
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MYOF myoferlin
NQO1 NAD(P)H dehydrogenase, quinone 1
NRCAM neuronal cell adhesion molecule
PGD phosphogluconate dehydrogenase
PXMP2 peroxisomal membrane protein 2, 22kDa
RAP1GAP RAP1 GTPase activating protein
RBPMS RNA binding protein with multiple splicing
RRAS2 related RAS viral (r-ras) oncogene homolog 2
S100P S100 calcium binding protein P
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TKT transketolase
TRIM16 tripartite motif containing 16
TSKU tsukushi, small leucine rich proteoglycan
TXNRD1 thioredoxin reductase 1
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ADGRL2 adhesion G protein-coupled receptor L2
BCHE butyrylcholinesterase
DLC1 DLC1 Rho GTPase activating protein
FN1 fibronectin 1
FPGS folylpolyglutamate synthase
GNAS GNAS complex locus
GSTM3 glutathione S-transferase mu 3 (brain)
IFI27 interferon, alpha-inducible protein 27
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MEIS1 Meis homeobox 1
MNAT1 MNAT CDK-activating kinase assembly factor 1
PAEP progestagen-associated endometrial protein
PLAT plasminogen activator, tissue
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PRDX2 peroxiredoxin 2
SDC2 syndecan 2
SPINK1 serine peptidase inhibitor, Kazal type 1
TFPI2 tissue factor pathway inhibitor 2