BRD-K67870070_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

87 genes differentially expressed following the BRD-K67870070_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABLIM1 actin binding LIM protein 1
ACOT9 acyl-CoA thioesterase 9
ANXA1 annexin A1
ANXA2P2 annexin A2 pseudogene 2
ANXA3 annexin A3
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ATF3 activating transcription factor 3
CAB39 calcium binding protein 39
CD58 CD58 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DUSP14 dual specificity phosphatase 14
DUSP3 dual specificity phosphatase 3
DUSP5 dual specificity phosphatase 5
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
EMP1 epithelial membrane protein 1
EZR ezrin
F3 coagulation factor III (thromboplastin, tissue factor)
FABP4 fatty acid binding protein 4, adipocyte
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FHL2 four and a half LIM domains 2
FKBP1B FK506 binding protein 1B, 12.6 kDa
FLNA filamin A, alpha
FOSL1 FOS-like antigen 1
GLS glutaminase
GPRC5A G protein-coupled receptor, class C, group 5, member A
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
ILK integrin-linked kinase
INHBB inhibin, beta B
INSIG1 insulin induced gene 1
KLF6 Kruppel-like factor 6
KRT6B keratin 6B, type II
LDLR low density lipoprotein receptor
LMO2 LIM domain only 2 (rhombotin-like 1)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MSMO1 methylsterol monooxygenase 1
OGFRL1 opioid growth factor receptor-like 1
PDE2A phosphodiesterase 2A, cGMP-stimulated
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PPARD peroxisome proliferator-activated receptor delta
RHOB ras homolog family member B
RRAS2 related RAS viral (r-ras) oncogene homolog 2
S100A10 S100 calcium binding protein A10
SAT1 spermidine/spermine N1-acetyltransferase 1
SFN stratifin
SMS spermine synthase
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SOX9 SRY (sex determining region Y)-box 9
SWAP70 SWAP switching B-cell complex 70kDa subunit
TACSTD2 tumor-associated calcium signal transducer 2
TGFA transforming growth factor, alpha
TICAM1 toll-like receptor adaptor molecule 1
TJP1 tight junction protein 1
TM4SF1 transmembrane 4 L six family member 1
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TPM1 tropomyosin 1 (alpha)
TRIO trio Rho guanine nucleotide exchange factor
TSPAN1 tetraspanin 1
TSPAN4 tetraspanin 4
TUBB2A tubulin, beta 2A class IIa
TUFT1 tuftelin 1
VIM vimentin
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta

decreased expression

Symbol Name
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
C14ORF132 chromosome 14 open reading frame 132
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CP ceruloplasmin (ferroxidase)
H2BFS H2B histone family, member S (pseudogene)
HOXA10 homeobox A10
IGHM immunoglobulin heavy constant mu
KIF20A kinesin family member 20A
MAN1C1 mannosidase, alpha, class 1C, member 1
MAOB monoamine oxidase B
MTSS1 metastasis suppressor 1
NEFH neurofilament, heavy polypeptide
OBSL1 obscurin-like 1
PCSK1 proprotein convertase subtilisin/kexin type 1
PEG10 paternally expressed 10
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PSRC1 proline/serine-rich coiled-coil 1
S100P S100 calcium binding protein P
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
TPR translocated promoter region, nuclear basket protein
ZIC1 Zic family member 1