BRD-K67868012_PI-103_SKBR3_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

89 genes differentially expressed following the BRD-K67868012_PI-103_SKBR3_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACOT13 acyl-CoA thioesterase 13
AKAP9 A kinase (PRKA) anchor protein 9
BCL6 B-cell CLL/lymphoma 6
C1QB complement component 1, q subcomponent, B chain
C6ORF48 chromosome 6 open reading frame 48
C6ORF62 chromosome 6 open reading frame 62
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CD163 CD163 molecule
CD44 CD44 molecule (Indian blood group)
CD52 CD52 molecule
CFD complement factor D (adipsin)
COBL cordon-bleu WH2 repeat protein
COL5A2 collagen, type V, alpha 2
FAM13A family with sequence similarity 13, member A
GABARAPL1 GABA(A) receptor-associated protein like 1
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GRB7 growth factor receptor-bound protein 7
HBP1 HMG-box transcription factor 1
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IL7R interleukin 7 receptor
KIAA0355 KIAA0355
KIAA1033 KIAA1033
KRT18 keratin 18, type I
LEF1 lymphoid enhancer-binding factor 1
LPL lipoprotein lipase
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MBNL2 muscleblind-like splicing regulator 2
METTL7A methyltransferase like 7A
MID1 midline 1
MME membrane metallo-endopeptidase
NT5E 5'-nucleotidase, ecto (CD73)
PEG10 paternally expressed 10
PERP PERP, TP53 apoptosis effector
PLTP phospholipid transfer protein
PPARG peroxisome proliferator-activated receptor gamma
PTN pleiotrophin
RAB13 RAB13, member RAS oncogene family
RBP4 retinol binding protein 4, plasma
RPS26 ribosomal protein S26
SAT1 spermidine/spermine N1-acetyltransferase 1
SLC39A8 solute carrier family 39 (zinc transporter), member 8
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TMEM135 transmembrane protein 135
TSC22D1 TSC22 domain family, member 1
TSC22D3 TSC22 domain family, member 3
TSPAN4 tetraspanin 4
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)

decreased expression

Symbol Name
ADO 2-aminoethanethiol (cysteamine) dioxygenase
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
BRD2 bromodomain containing 2
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCL2 chemokine (C-C motif) ligand 2
CCR2 chemokine (C-C motif) receptor 2
CDC25A cell division cycle 25A
CFAP20 cilia and flagella associated protein 20
CTSH cathepsin H
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
FAS Fas cell surface death receptor
GATA6 GATA binding protein 6
GLS glutaminase
HSPA1A heat shock 70kDa protein 1A
KLF4 Kruppel-like factor 4 (gut)
MAT2A methionine adenosyltransferase II, alpha
NKX3-1 NK3 homeobox 1
PCP4 Purkinje cell protein 4
PIEZO2 piezo-type mechanosensitive ion channel component 2
PLAC8 placenta-specific 8
PPIF peptidylprolyl isomerase F
PROM1 prominin 1
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAD51C RAD51 paralog C
REEP1 receptor accessory protein 1
RRP15 ribosomal RNA processing 15 homolog (S. cerevisiae)
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SNAP25 synaptosomal-associated protein, 25kDa
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
STMN2 stathmin 2
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae)
THBS1 thrombospondin 1
TLR4 toll-like receptor 4
TSC22D2 TSC22 domain family, member 2