BRD-K67868012_PI-103_SKBR3_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

73 genes differentially expressed following the BRD-K67868012_PI-103_SKBR3_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADCK2 aarF domain containing kinase 2
AGR2 anterior gradient 2
AHCY adenosylhomocysteinase
APLP2 amyloid beta (A4) precursor-like protein 2
BCL2L1 BCL2-like 1
C1QB complement component 1, q subcomponent, B chain
CD93 CD93 molecule
CDH5 cadherin 5, type 2 (vascular endothelium)
CH25H cholesterol 25-hydroxylase
CLCA2 chloride channel accessory 2
EFNB2 ephrin-B2
EPN2 epsin 2
F13A1 coagulation factor XIII, A1 polypeptide
FABP4 fatty acid binding protein 4, adipocyte
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
H1F0 H1 histone family, member 0
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MAN2A1 mannosidase, alpha, class 2A, member 1
MGP matrix Gla protein
MICALL1 MICAL-like 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PLTP phospholipid transfer protein
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
S100P S100 calcium binding protein P
SFTPA2 surfactant protein A2
SFTPC surfactant protein C
SPATA20 spermatogenesis associated 20
SRPX2 sushi-repeat containing protein, X-linked 2
STXBP2 syntaxin binding protein 2
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFF3 trefoil factor 3 (intestinal)
TFPI2 tissue factor pathway inhibitor 2
VWF von Willebrand factor
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
AURKA aurora kinase A
BAG2 BCL2-associated athanogene 2
CCNA2 cyclin A2
CENPA centromere protein A
CEP55 centrosomal protein 55kDa
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CXCL11 chemokine (C-X-C motif) ligand 11
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
ENC1 ectodermal-neural cortex 1 (with BTB domain)
GATA6 GATA binding protein 6
GUSBP11 glucuronidase, beta pseudogene 11
HOXA10 homeobox A10
HOXA11 homeobox A11
HSPA1A heat shock 70kDa protein 1A
IGHM immunoglobulin heavy constant mu
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
INA internexin neuronal intermediate filament protein, alpha
KIF20A kinesin family member 20A
KIF23 kinesin family member 23
NDC80 NDC80 kinetochore complex component
NEFH neurofilament, heavy polypeptide
NPDC1 neural proliferation, differentiation and control, 1
NRG1 neuregulin 1
OIP5 Opa interacting protein 5
OLFM4 olfactomedin 4
PBK PDZ binding kinase
PLK1 polo-like kinase 1
POU2AF1 POU class 2 associating factor 1
RGS2 regulator of G-protein signaling 2
TRBC1 T cell receptor beta constant 1