BRD-K67868012_PI-103_HS578T_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

94 genes differentially expressed following the BRD-K67868012_PI-103_HS578T_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AMIGO2 adhesion molecule with Ig-like domain 2
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
COL10A1 collagen, type X, alpha 1
COMP cartilage oligomeric matrix protein
DAPK1 death-associated protein kinase 1
DPP4 dipeptidyl-peptidase 4
DUSP6 dual specificity phosphatase 6
EPHA3 EPH receptor A3
FAM129A family with sequence similarity 129, member A
FAM171A1 family with sequence similarity 171, member A1
FLRT2 fibronectin leucine rich transmembrane protein 2
FSCN1 fascin actin-bundling protein 1
GAS1 growth arrest-specific 1
GUCY1B3 guanylate cyclase 1, soluble, beta 3
HLF hepatic leukemia factor
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
KCTD12 potassium channel tetramerization domain containing 12
LAPTM4B lysosomal protein transmembrane 4 beta
LPAR6 lysophosphatidic acid receptor 6
LYPD1 LY6/PLAUR domain containing 1
MAMLD1 mastermind-like domain containing 1
METTL7A methyltransferase like 7A
NLGN4X neuroligin 4, X-linked
NT5E 5'-nucleotidase, ecto (CD73)
PBX3 pre-B-cell leukemia homeobox 3
PDGFC platelet derived growth factor C
PRPS2 phosphoribosyl pyrophosphate synthetase 2
SFTPB surfactant protein B
SLC35F2 solute carrier family 35, member F2
SOX4 SRY (sex determining region Y)-box 4
SPON1 spondin 1, extracellular matrix protein
THAP11 THAP domain containing 11
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
WT1 Wilms tumor 1
ZMAT3 zinc finger, matrin-type 3

decreased expression

Symbol Name
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain
ADM adrenomedullin
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
AREG amphiregulin
CA12 carbonic anhydrase XII
CA2 carbonic anhydrase II
CALML3 calmodulin-like 3
CD24 CD24 molecule
CDC25A cell division cycle 25A
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
COG5 component of oligomeric golgi complex 5
CRIP1 cysteine-rich protein 1 (intestinal)
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL3 chemokine (C-X-C motif) ligand 3
DDIT4 DNA-damage-inducible transcript 4
DIO2 deiodinase, iodothyronine, type II
FKBP11 FK506 binding protein 11, 19 kDa
GJA1 gap junction protein, alpha 1, 43kDa
GPRC5A G protein-coupled receptor, class C, group 5, member A
GRIA2 glutamate receptor, ionotropic, AMPA 2
GRWD1 glutamate-rich WD repeat containing 1
HILPDA hypoxia inducible lipid droplet-associated
IGFBP5 insulin-like growth factor binding protein 5
KRT15 keratin 15, type I
KRT6B keratin 6B, type II
LAMA3 laminin, alpha 3
LOX lysyl oxidase
MAT2A methionine adenosyltransferase II, alpha
MBP myelin basic protein
MT1X metallothionein 1X
NAMPT nicotinamide phosphoribosyltransferase
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NRCAM neuronal cell adhesion molecule
PI3 peptidase inhibitor 3, skin-derived
PLP1 proteolipid protein 1
PPAP2B phosphatidic acid phosphatase type 2B
PUS7 pseudouridylate synthase 7 (putative)
RAB25 RAB25, member RAS oncogene family
RCAN1 regulator of calcineurin 1
RGS4 regulator of G-protein signaling 4
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC16A6 solute carrier family 16, member 6
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STC1 stanniocalcin 1
SYBU syntabulin (syntaxin-interacting)
TFF3 trefoil factor 3 (intestinal)
TMEM164 transmembrane protein 164
TNNC1 troponin C type 1 (slow)
TSPAN7 tetraspanin 7
TUBB2A tubulin, beta 2A class IIa