BRD-K67868012_PI-103_HME1_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

83 genes differentially expressed following the BRD-K67868012_PI-103_HME1_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKAP13 A kinase (PRKA) anchor protein 13
AMIGO2 adhesion molecule with Ig-like domain 2
ARID5B AT rich interactive domain 5B (MRF1-like)
ATF3 activating transcription factor 3
BCL6 B-cell CLL/lymphoma 6
BPGM 2,3-bisphosphoglycerate mutase
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CD44 CD44 molecule (Indian blood group)
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CHIC2 cysteine-rich hydrophobic domain 2
DUSP6 dual specificity phosphatase 6
EGR1 early growth response 1
ETV1 ets variant 1
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GBP2 guanylate binding protein 2, interferon-inducible
HBP1 HMG-box transcription factor 1
HMGB2 high mobility group box 2
IFITM1 interferon induced transmembrane protein 1
KDM3A lysine (K)-specific demethylase 3A
KIAA1033 KIAA1033
KLHL21 kelch-like family member 21
KYNU kynureninase
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MET MET proto-oncogene, receptor tyrosine kinase
MPPED2 metallophosphoesterase domain containing 2
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NES nestin
PRKCH protein kinase C, eta
PTN pleiotrophin
RABGAP1L RAB GTPase activating protein 1-like
RGCC regulator of cell cycle
RGS10 regulator of G-protein signaling 10
SAT1 spermidine/spermine N1-acetyltransferase 1
SATB1 SATB homeobox 1
SPATS2L spermatogenesis associated, serine-rich 2-like
TBL1X transducin (beta)-like 1X-linked
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TSC22D3 TSC22 domain family, member 3
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
BEX1 brain expressed, X-linked 1
BEX4 brain expressed, X-linked 4
CDC25A cell division cycle 25A
CHGB chromogranin B
CREB1 cAMP responsive element binding protein 1
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CSTA cystatin A (stefin A)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
EREG epiregulin
FHL1 four and a half LIM domains 1
FKBP1B FK506 binding protein 1B, 12.6 kDa
G0S2 G0/G1 switch 2
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
HBB hemoglobin, beta
HP haptoglobin
HSPA1A heat shock 70kDa protein 1A
IL1B interleukin 1, beta
IL1R2 interleukin 1 receptor, type II
IL1RN interleukin 1 receptor antagonist
JMJD6 jumonji domain containing 6
LAMP3 lysosomal-associated membrane protein 3
LAPTM4B lysosomal protein transmembrane 4 beta
LTF lactotransferrin
MAT2A methionine adenosyltransferase II, alpha
MTERF3 mitochondrial transcription termination factor 3
NOP16 NOP16 nucleolar protein
NRN1 neuritin 1
PLBD1 phospholipase B domain containing 1
PLIN2 perilipin 2
PNN pinin, desmosome associated protein
PPIF peptidylprolyl isomerase F
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PSAT1 phosphoserine aminotransferase 1
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SNAP25 synaptosomal-associated protein, 25kDa
TMEM70 transmembrane protein 70
XIST X inactive specific transcript (non-protein coding)