BRD-K67868012_PI-103_HA1E_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

115 genes differentially expressed following the BRD-K67868012_PI-103_HA1E_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
AQP3 aquaporin 3 (Gill blood group)
ARID5B AT rich interactive domain 5B (MRF1-like)
ATP9A ATPase, class II, type 9A
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
C10ORF10 chromosome 10 open reading frame 10
CD44 CD44 molecule (Indian blood group)
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CNPY3 canopy FGF signaling regulator 3
COL3A1 collagen, type III, alpha 1
CXADR coxsackie virus and adenovirus receptor
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DPYSL3 dihydropyrimidinase-like 3
DUSP6 dual specificity phosphatase 6
EDN1 endothelin 1
FABP4 fatty acid binding protein 4, adipocyte
FILIP1L filamin A interacting protein 1-like
FXYD3 FXYD domain containing ion transport regulator 3
GADD45B growth arrest and DNA-damage-inducible, beta
GJA1 gap junction protein, alpha 1, 43kDa
GPX2 glutathione peroxidase 2
HMGB3 high mobility group box 3
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IRS2 insulin receptor substrate 2
ITGB5 integrin, beta 5
KIAA0355 KIAA0355
KLF6 Kruppel-like factor 6
KRT6B keratin 6B, type II
LGALS4 lectin, galactoside-binding, soluble, 4
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MUC5B mucin 5B, oligomeric mucus/gel-forming
OPTN optineurin
OSBPL1A oxysterol binding protein-like 1A
OXTR oxytocin receptor
PAM peptidylglycine alpha-amidating monooxygenase
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PAWR PRKC, apoptosis, WT1, regulator
POSTN periostin, osteoblast specific factor
PROM1 prominin 1
RAB4A RAB4A, member RAS oncogene family
S100P S100 calcium binding protein P
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SOX4 SRY (sex determining region Y)-box 4
SPRY2 sprouty homolog 2 (Drosophila)
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TM4SF1 transmembrane 4 L six family member 1
TMSB15A thymosin beta 15a
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TSPAN8 tetraspanin 8
VAT1 vesicle amine transport 1
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABHD6 abhydrolase domain containing 6
ACKR3 atypical chemokine receptor 3
ADGRG1 adhesion G protein-coupled receptor G1
ADI1 acireductone dioxygenase 1
AK4 adenylate kinase 4
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDOC aldolase C, fructose-bisphosphate
ANPEP alanyl (membrane) aminopeptidase
ATG3 autophagy related 3
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CA12 carbonic anhydrase XII
CLU clusterin
CTSZ cathepsin Z
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT4 DNA-damage-inducible transcript 4
DHRS2 dehydrogenase/reductase (SDR family) member 2
EMP3 epithelial membrane protein 3
ESR1 estrogen receptor 1
FAM162A family with sequence similarity 162, member A
HHEX hematopoietically expressed homeobox
HILPDA hypoxia inducible lipid droplet-associated
HIST1H2BK histone cluster 1, H2bk
HMOX1 heme oxygenase 1
IGFBP3 insulin-like growth factor binding protein 3
IGFBP5 insulin-like growth factor binding protein 5
LTF lactotransferrin
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1X metallothionein 1X
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NRCAM neuronal cell adhesion molecule
PAX8 paired box 8
PDIA3 protein disulfide isomerase family A, member 3
PGM1 phosphoglucomutase 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PRAME preferentially expressed antigen in melanoma
RAD23B RAD23 homolog B (S. cerevisiae)
RHOC ras homolog family member C
SCARB1 scavenger receptor class B, member 1
SFRP1 secreted frizzled-related protein 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SORD sorbitol dehydrogenase
SPAG4 sperm associated antigen 4
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
STC1 stanniocalcin 1
TBX3 T-box 3
TG thyroglobulin
TKTL1 transketolase-like 1
WNT5A wingless-type MMTV integration site family, member 5A