BRD-K67868012_PI-103_BT20_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

55 genes differentially expressed following the BRD-K67868012_PI-103_BT20_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
APOD apolipoprotein D
ARID5B AT rich interactive domain 5B (MRF1-like)
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
BCL6 B-cell CLL/lymphoma 6
CCNG2 cyclin G2
CLEC2B C-type lectin domain family 2, member B
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
CTGF connective tissue growth factor
DST dystonin
FABP4 fatty acid binding protein 4, adipocyte
FAM129A family with sequence similarity 129, member A
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
KDM3A lysine (K)-specific demethylase 3A
MYBPC1 myosin binding protein C, slow type
OXTR oxytocin receptor
PIP prolactin-induced protein
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLIN2 perilipin 2
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SFRP1 secreted frizzled-related protein 1
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SOX4 SRY (sex determining region Y)-box 4
STS steroid sulfatase (microsomal), isozyme S
SVIL supervillin
SYNM synemin, intermediate filament protein
TCF4 transcription factor 4
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
THBS4 thrombospondin 4
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
BHLHE40 basic helix-loop-helix family, member e40
CCND2 cyclin D2
CD24 CD24 molecule
CDC25A cell division cycle 25A
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CTSZ cathepsin Z
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP4 dual specificity phosphatase 4
FOSL1 FOS-like antigen 1
GADD45A growth arrest and DNA-damage-inducible, alpha
HBEGF heparin-binding EGF-like growth factor
IER3 immediate early response 3
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKV3-20 immunoglobulin kappa variable 3-20
IGL immunoglobulin lambda locus
NOP56 NOP56 ribonucleoprotein
PGBD5 piggyBac transposable element derived 5
PHLDA2 pleckstrin homology-like domain, family A, member 2
S100A6 S100 calcium binding protein A6
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SFN stratifin
SNAP25 synaptosomal-associated protein, 25kDa
VSNL1 visinin-like 1