BRD-K67860401_GSK-3b Inhibitor VIII_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

113 genes differentially expressed following the BRD-K67860401_GSK-3b Inhibitor VIII_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
AEBP1 AE binding protein 1
ANGPT1 angiopoietin 1
ANXA10 annexin A10
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
AREG amphiregulin
ARHGAP29 Rho GTPase activating protein 29
ASPN asporin
ATF3 activating transcription factor 3
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CCL4 chemokine (C-C motif) ligand 4
CCL8 chemokine (C-C motif) ligand 8
CCND2 cyclin D2
CD52 CD52 molecule
CD83 CD83 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CLDN7 claudin 7
COL5A2 collagen, type V, alpha 2
CPE carboxypeptidase E
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DPT dermatopontin
EGFL6 EGF-like-domain, multiple 6
EMP1 epithelial membrane protein 1
EPCAM epithelial cell adhesion molecule
FAM171A1 family with sequence similarity 171, member A1
FBLN1 fibulin 1
FN1 fibronectin 1
G0S2 G0/G1 switch 2
GLUL glutamate-ammonia ligase
GPNMB glycoprotein (transmembrane) nmb
GRHL2 grainyhead-like 2 (Drosophila)
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IDO1 indoleamine 2,3-dioxygenase 1
ITM2A integral membrane protein 2A
KRT19 keratin 19, type I
LY6E lymphocyte antigen 6 complex, locus E
MECOM MDS1 and EVI1 complex locus
MMP9 matrix metallopeptidase 9
MT1M metallothionein 1M
NELL2 NEL-like 2 (chicken)
NPR3 natriuretic peptide receptor 3
NR4A3 nuclear receptor subfamily 4, group A, member 3
PCP4 Purkinje cell protein 4
PDE9A phosphodiesterase 9A
PEG3 paternally expressed 3
RAB25 RAB25, member RAS oncogene family
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RBP1 retinol binding protein 1, cellular
RBP4 retinol binding protein 4, plasma
RGS1 regulator of G-protein signaling 1
SCGB2A1 secretoglobin, family 2A, member 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SORBS2 sorbin and SH3 domain containing 2
SPARCL1 SPARC-like 1 (hevin)
TIMP3 TIMP metallopeptidase inhibitor 3
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM30B transmembrane protein 30B
TPD52L1 tumor protein D52-like 1
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
TXNIP thioredoxin interacting protein
VNN1 vanin 1

decreased expression

Symbol Name
AGRN agrin
AK4 adenylate kinase 4
AZU1 azurocidin 1
C6ORF62 chromosome 6 open reading frame 62
CALR calreticulin
CANX calnexin
CDCA4 cell division cycle associated 4
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CHN1 chimerin 1
DHCR24 24-dehydrocholesterol reductase
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
EIF3K eukaryotic translation initiation factor 3, subunit K
EIF5 eukaryotic translation initiation factor 5
ELANE elastase, neutrophil expressed
ERBB2 erb-b2 receptor tyrosine kinase 2
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GLS glutaminase
HSPA2 heat shock 70kDa protein 2
INSIG1 insulin induced gene 1
KIF14 kinesin family member 14
LYPLA1 lysophospholipase I
MARCKS myristoylated alanine-rich protein kinase C substrate
MBNL2 muscleblind-like splicing regulator 2
MFSD10 major facilitator superfamily domain containing 10
NREP neuronal regeneration related protein
OXA1L oxidase (cytochrome c) assembly 1-like
OXTR oxytocin receptor
PDGFD platelet derived growth factor D
PLAT plasminogen activator, tissue
PON2 paraoxonase 2
PPIC peptidylprolyl isomerase C (cyclophilin C)
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2
PRKCA protein kinase C, alpha
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
STXBP2 syntaxin binding protein 2
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TM4SF1 transmembrane 4 L six family member 1
TMEM45A transmembrane protein 45A
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNS3 tensin 3
UBE3C ubiquitin protein ligase E3C
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)