BRD-K67847053_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

72 genes differentially expressed following the BRD-K67847053_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AMDHD2 amidohydrolase domain containing 2
AMIGO2 adhesion molecule with Ig-like domain 2
ANXA1 annexin A1
ARID5B AT rich interactive domain 5B (MRF1-like)
ATHL1 ATH1, acid trehalase-like 1 (yeast)
BHLHE41 basic helix-loop-helix family, member e41
BIRC2 baculoviral IAP repeat containing 2
CALD1 caldesmon 1
CD9 CD9 molecule
CDK14 cyclin-dependent kinase 14
CNPY3 canopy FGF signaling regulator 3
COL1A2 collagen, type I, alpha 2
COL6A1 collagen, type VI, alpha 1
COL8A2 collagen, type VIII, alpha 2
CRELD2 cysteine-rich with EGF-like domains 2
CYBB cytochrome b-245, beta polypeptide
DKK3 dickkopf WNT signaling pathway inhibitor 3
DRAM1 DNA-damage regulated autophagy modulator 1
FCHO1 FCH domain only 1
GPC4 glypican 4
HBB hemoglobin, beta
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
IGFBP5 insulin-like growth factor binding protein 5
KCTD12 potassium channel tetramerization domain containing 12
KLF13 Kruppel-like factor 13
LIMCH1 LIM and calponin homology domains 1
LPAR6 lysophosphatidic acid receptor 6
MMP7 matrix metallopeptidase 7
MNDA myeloid cell nuclear differentiation antigen
MSLN mesothelin
MYO6 myosin VI
MYOF myoferlin
NARFL nuclear prelamin A recognition factor-like
PDE4B phosphodiesterase 4B, cAMP-specific
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
RFC5 replication factor C (activator 1) 5, 36.5kDa
RIN2 Ras and Rab interactor 2
S100A8 S100 calcium binding protein A8
SHB Src homology 2 domain containing adaptor protein B
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SRRM2 serine/arginine repetitive matrix 2
SUSD4 sushi domain containing 4
TLR4 toll-like receptor 4
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
UBXN4 UBX domain protein 4
VIM vimentin
VTCN1 V-set domain containing T cell activation inhibitor 1
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AK1 adenylate kinase 1
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AREG amphiregulin
AVPI1 arginine vasopressin-induced 1
BCHE butyrylcholinesterase
CASP7 caspase 7, apoptosis-related cysteine peptidase
FABP5 fatty acid binding protein 5 (psoriasis-associated)
GPX2 glutathione peroxidase 2
IFI27 interferon, alpha-inducible protein 27
IGFBP4 insulin-like growth factor binding protein 4
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial
PLAGL1 pleiomorphic adenoma gene-like 1
PRDX2 peroxiredoxin 2
RPL37A ribosomal protein L37a
SPATS2L spermatogenesis associated, serine-rich 2-like
TFF3 trefoil factor 3 (intestinal)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGM2 transglutaminase 2