BRD-K67808578_1391-0741_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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46 genes differentially expressed following the BRD-K67808578_1391-0741_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
EMX2 empty spiracles homeobox 2
FGG fibrinogen gamma chain
GPER1 G protein-coupled estrogen receptor 1
HMOX1 heme oxygenase 1
IGFBP3 insulin-like growth factor binding protein 3
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
NRCAM neuronal cell adhesion molecule
OLFML2A olfactomedin-like 2A
SLC39A8 solute carrier family 39 (zinc transporter), member 8
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TYRP1 tyrosinase-related protein 1

decreased expression

Symbol Name
ANPEP alanyl (membrane) aminopeptidase
APOD apolipoprotein D
CCL19 chemokine (C-C motif) ligand 19
CFB complement factor B
CST3 cystatin C
CSTA cystatin A (stefin A)
FBXO21 F-box protein 21
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
IGF1R insulin-like growth factor 1 receptor
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IL6ST interleukin 6 signal transducer
KLK2 kallikrein-related peptidase 2
KLK3 kallikrein-related peptidase 3
KRT15 keratin 15, type I
LXN latexin
MAOA monoamine oxidase A
MAOB monoamine oxidase B
MSMB microseminoprotein, beta-
NDRG1 N-myc downstream regulated 1
NET1 neuroepithelial cell transforming 1
NKX3-1 NK3 homeobox 1
OLFM4 olfactomedin 4
PCP4 Purkinje cell protein 4
PLA2G16 phospholipase A2, group XVI
PTGDS prostaglandin D2 synthase 21kDa (brain)
RAP1GAP RAP1 GTPase activating protein
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RTN1 reticulon 1
SLC44A4 solute carrier family 44, member 4
SPDEF SAM pointed domain containing ETS transcription factor
TACSTD2 tumor-associated calcium signal transducer 2
TM4SF1 transmembrane 4 L six family member 1