BRD-K67566344_KU-0063794_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

47 genes differentially expressed following the BRD-K67566344_KU-0063794_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRE5 adhesion G protein-coupled receptor E5
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
CCNG2 cyclin G2
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
FOXO3 forkhead box O3
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
IGFBP3 insulin-like growth factor binding protein 3
MGLL monoglyceride lipase
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFIB nuclear factor I/B
PRSS23 protease, serine, 23
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
VCAN versican
WDR45 WD repeat domain 45
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CALU calumenin
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CLTB clathrin, light chain B
CYB5A cytochrome b5 type A (microsomal)
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
ELANE elastase, neutrophil expressed
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GCLM glutamate-cysteine ligase, modifier subunit
GJA1 gap junction protein, alpha 1, 43kDa
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HSPH1 heat shock 105kDa/110kDa protein 1
ICMT isoprenylcysteine carboxyl methyltransferase
LAPTM4B lysosomal protein transmembrane 4 beta
LSM1 LSM1, U6 small nuclear RNA associated
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
NT5DC2 5'-nucleotidase domain containing 2
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
SDC2 syndecan 2
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SLPI secretory leukocyte peptidase inhibitor
SRGN serglycin
STIP1 stress-induced phosphoprotein 1
TLR4 toll-like receptor 4
TM9SF2 transmembrane 9 superfamily member 2
UFD1L ubiquitin fusion degradation 1 like (yeast)