BRD-K67537649_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

71 genes differentially expressed following the BRD-K67537649_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR1 atypical chemokine receptor 1 (Duffy blood group)
BACE2 beta-site APP-cleaving enzyme 2
BIRC3 baculoviral IAP repeat containing 3
CAB39 calcium binding protein 39
COCH cochlin
COL14A1 collagen, type XIV, alpha 1
COL9A3 collagen, type IX, alpha 3
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CRY1 cryptochrome circadian clock 1
DDIT4 DNA-damage-inducible transcript 4
DUSP5 dual specificity phosphatase 5
EIF5A eukaryotic translation initiation factor 5A
FAM57A family with sequence similarity 57, member A
FLNA filamin A, alpha
FOSL1 FOS-like antigen 1
FSD1 fibronectin type III and SPRY domain containing 1
H1F0 H1 histone family, member 0
HOMER1 homer scaffolding protein 1
HOOK2 hook microtubule-tethering protein 2
HSPA1A heat shock 70kDa protein 1A
IER3 immediate early response 3
KRT14 keratin 14, type I
KRT17 keratin 17, type I
KRT18 keratin 18, type I
KRT6B keratin 6B, type II
LAMC1 laminin, gamma 1 (formerly LAMB2)
LPL lipoprotein lipase
LY6D lymphocyte antigen 6 complex, locus D
MCL1 myeloid cell leukemia 1
MICALL1 MICAL-like 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PI3 peptidase inhibitor 3, skin-derived
PLTP phospholipid transfer protein
RBM47 RNA binding motif protein 47
RHCG Rh family, C glycoprotein
RPL38 ribosomal protein L38
RPS11 ribosomal protein S11
S100A2 S100 calcium binding protein A2
S100A7 S100 calcium binding protein A7
SFRP1 secreted frizzled-related protein 1
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SORBS1 sorbin and SH3 domain containing 1
SOX4 SRY (sex determining region Y)-box 4
SYNM synemin, intermediate filament protein
TMEM45A transmembrane protein 45A
TNC tenascin C
XPO7 exportin 7

decreased expression

Symbol Name
AKR1C3 aldo-keto reductase family 1, member C3
ANGPT1 angiopoietin 1
ANXA1 annexin A1
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CEP70 centrosomal protein 70kDa
CPE carboxypeptidase E
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
GSTA1 glutathione S-transferase alpha 1
HBB hemoglobin, beta
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HOXB6 homeobox B6
IDI1 isopentenyl-diphosphate delta isomerase 1
IKZF1 IKAROS family zinc finger 1 (Ikaros)
INSIG1 insulin induced gene 1
LMO3 LIM domain only 3 (rhombotin-like 2)
LOX lysyl oxidase
MSMO1 methylsterol monooxygenase 1
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SULF1 sulfatase 1
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TRD T cell receptor delta locus
XIST X inactive specific transcript (non-protein coding)