BRD-K67537649_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

40 genes differentially expressed following the BRD-K67537649_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ASS1 argininosuccinate synthase 1
ATF3 activating transcription factor 3
ATF4 activating transcription factor 4
CDK6 cyclin-dependent kinase 6
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
DUSP4 dual specificity phosphatase 4
EGR3 early growth response 3
FABP4 fatty acid binding protein 4, adipocyte
FABP7 fatty acid binding protein 7, brain
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
IER5 immediate early response 5
IFRD1 interferon-related developmental regulator 1
JUNB jun B proto-oncogene
KLF6 Kruppel-like factor 6
LDLR low density lipoprotein receptor
LOC100505650 uncharacterized LOC100505650
LPIN1 lipin 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAST4 microtubule associated serine/threonine kinase family member 4
MYBPC1 myosin binding protein C, slow type
PDE4B phosphodiesterase 4B, cAMP-specific
PHGDH phosphoglycerate dehydrogenase
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PSAT1 phosphoserine aminotransferase 1
PYGL phosphorylase, glycogen, liver
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RNF19B ring finger protein 19B
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SFRP1 secreted frizzled-related protein 1
SFRP4 secreted frizzled-related protein 4

decreased expression

Symbol Name
CA12 carbonic anhydrase XII
HIST1H4C histone cluster 1, H4c
HOXB2 homeobox B2
MAGEA3 melanoma antigen family A3
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative)