BRD-K67519589_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

98 genes differentially expressed following the BRD-K67519589_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL3 acyl-CoA synthetase long-chain family member 3
ANXA1 annexin A1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BZW2 basic leucine zipper and W2 domains 2
CAV1 caveolin 1, caveolae protein, 22kDa
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
COL11A1 collagen, type XI, alpha 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL9 chemokine (C-X-C motif) ligand 9
DEPTOR DEP domain containing MTOR-interacting protein
DSP desmoplakin
FYB FYN binding protein
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
HBB hemoglobin, beta
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HHEX hematopoietically expressed homeobox
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IGFBP5 insulin-like growth factor binding protein 5
IKZF1 IKAROS family zinc finger 1 (Ikaros)
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KIAA1033 KIAA1033
KRT14 keratin 14, type I
KRT15 keratin 15, type I
KRT7 keratin 7, type II
LEF1 lymphoid enhancer-binding factor 1
LMO2 LIM domain only 2 (rhombotin-like 1)
LPAR6 lysophosphatidic acid receptor 6
LUM lumican
MAN1A1 mannosidase, alpha, class 1A, member 1
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MYB v-myb avian myeloblastosis viral oncogene homolog
NARFL nuclear prelamin A recognition factor-like
OPN3 opsin 3
PDE4B phosphodiesterase 4B, cAMP-specific
PRKCQ protein kinase C, theta
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SERINC5 serine incorporator 5
SH3BP4 SH3-domain binding protein 4
SPTSSA serine palmitoyltransferase, small subunit A
SULF1 sulfatase 1
TACSTD2 tumor-associated calcium signal transducer 2
TARBP1 TAR (HIV-1) RNA binding protein 1
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TLR4 toll-like receptor 4
TRIM22 tripartite motif containing 22
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C
VEGFA vascular endothelial growth factor A
VSNL1 visinin-like 1
XBP1 X-box binding protein 1
ZBED2 zinc finger, BED-type containing 2

decreased expression

Symbol Name
ANXA6 annexin A6
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa
ATF3 activating transcription factor 3
B3GNT1
BST2 bone marrow stromal cell antigen 2
CD99 CD99 molecule
CDC42 cell division cycle 42
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
COL14A1 collagen, type XIV, alpha 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DPP4 dipeptidyl-peptidase 4
FLNA filamin A, alpha
FOLR1 folate receptor 1 (adult)
GAL galanin/GMAP prepropeptide
HSPA8 heat shock 70kDa protein 8
IL17RB interleukin 17 receptor B
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KIAA0100 KIAA0100
LTBP3 latent transforming growth factor beta binding protein 3
MAN2B1 mannosidase, alpha, class 2B, member 1
MICALL1 MICAL-like 1
MME membrane metallo-endopeptidase
MXRA7 matrix-remodelling associated 7
NT5DC2 5'-nucleotidase domain containing 2
NUDCD3 NudC domain containing 3
PLEC plectin
PLXNB2 plexin B2
PNMA1 paraneoplastic Ma antigen 1
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RFC2 replication factor C (activator 1) 2, 40kDa
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
SET SET nuclear proto-oncogene
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
SPATS2L spermatogenesis associated, serine-rich 2-like
SPINK1 serine peptidase inhibitor, Kazal type 1
SPON1 spondin 1, extracellular matrix protein
SRSF6 serine/arginine-rich splicing factor 6
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TPSB2 tryptase beta 2 (gene/pseudogene)
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)