BRD-K67506692_EI-263_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

103 genes differentially expressed following the BRD-K67506692_EI-263_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARG1 arginase 1
ATF3 activating transcription factor 3
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHI3L2 chitinase 3-like 2
CHIC2 cysteine-rich hydrophobic domain 2
COBL cordon-bleu WH2 repeat protein
CTSE cathepsin E
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
CYTL1 cytokine-like 1
DUSP6 dual specificity phosphatase 6
EFNB2 ephrin-B2
EGR1 early growth response 1
EGR2 early growth response 2
EGR3 early growth response 3
FAM46A family with sequence similarity 46, member A
FMO2 flavin containing monooxygenase 2 (non-functional)
FOLR1 folate receptor 1 (adult)
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GEM GTP binding protein overexpressed in skeletal muscle
GPX3 glutathione peroxidase 3
HAL histidine ammonia-lyase
HES1 hes family bHLH transcription factor 1
HMOX1 heme oxygenase 1
HOPX HOP homeobox
HP haptoglobin
IER2 immediate early response 2
IER3 immediate early response 3
IGFBP3 insulin-like growth factor binding protein 3
JUN jun proto-oncogene
JUNB jun B proto-oncogene
KAT6A K(lysine) acetyltransferase 6A
KAT6B K(lysine) acetyltransferase 6B
KCTD5 potassium channel tetramerization domain containing 5
KLF6 Kruppel-like factor 6
LIF leukemia inhibitory factor
LTF lactotransferrin
MAGEA3 melanoma antigen family A3
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFIB nuclear factor I/B
NOTCH2NL notch 2 N-terminal like
NPR3 natriuretic peptide receptor 3
PLIN2 perilipin 2
PXMP2 peroxisomal membrane protein 2, 22kDa
RGS2 regulator of G-protein signaling 2
RND3 Rho family GTPase 3
RPP38 ribonuclease P/MRP 38kDa subunit
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TSC22D2 TSC22 domain family, member 2
TXNRD1 thioredoxin reductase 1
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ANXA4 annexin A4
APOA1 apolipoprotein A-I
ASNS asparagine synthetase (glutamine-hydrolyzing)
BEX4 brain expressed, X-linked 4
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCND1 cyclin D1
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD9 CD9 molecule
CD93 CD93 molecule
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
CRABP2 cellular retinoic acid binding protein 2
CSTA cystatin A (stefin A)
CXCL5 chemokine (C-X-C motif) ligand 5
CYTIP cytohesin 1 interacting protein
FAM69A family with sequence similarity 69, member A
FBLN1 fibulin 1
GJA1 gap junction protein, alpha 1, 43kDa
HAT1 histone acetyltransferase 1
HLA-B major histocompatibility complex, class I, B
HLA-DRA major histocompatibility complex, class II, DR alpha
HSPA1A heat shock 70kDa protein 1A
ISYNA1 inositol-3-phosphate synthase 1
KRT5 keratin 5, type II
LAMB1 laminin, beta 1
LAPTM4B lysosomal protein transmembrane 4 beta
MFAP5 microfibrillar associated protein 5
NT5DC2 5'-nucleotidase domain containing 2
PBX3 pre-B-cell leukemia homeobox 3
PDE4B phosphodiesterase 4B, cAMP-specific
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PECAM1 platelet/endothelial cell adhesion molecule 1
PEG10 paternally expressed 10
PLAT plasminogen activator, tissue
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTGIS prostaglandin I2 (prostacyclin) synthase
RCAN2 regulator of calcineurin 2
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SEPT2 septin 2
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TMEM45A transmembrane protein 45A
TPM4 tropomyosin 4
TUBB6 tubulin, beta 6 class V
VCAN versican