BRD-K67439147_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

120 genes differentially expressed following the BRD-K67439147_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AMIGO2 adhesion molecule with Ig-like domain 2
APOC1 apolipoprotein C-I
AQP4 aquaporin 4
AXL AXL receptor tyrosine kinase
CA2 carbonic anhydrase II
CAPG capping protein (actin filament), gelsolin-like
CD36 CD36 molecule (thrombospondin receptor)
CD52 CD52 molecule
CD58 CD58 molecule
CD9 CD9 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CLU clusterin
CRYAB crystallin, alpha B
CST3 cystatin C
CXCL13 chemokine (C-X-C motif) ligand 13
DDIT4 DNA-damage-inducible transcript 4
DFNA5 deafness, autosomal dominant 5
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DUSP14 dual specificity phosphatase 14
EREG epiregulin
FABP4 fatty acid binding protein 4, adipocyte
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FADS2 fatty acid desaturase 2
FAS Fas cell surface death receptor
FGF2 fibroblast growth factor 2 (basic)
FHL1 four and a half LIM domains 1
FOSL1 FOS-like antigen 1
FTH1 ferritin, heavy polypeptide 1
G0S2 G0/G1 switch 2
GABARAPL1 GABA(A) receptor-associated protein like 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GPER1 G protein-coupled estrogen receptor 1
GPR183 G protein-coupled receptor 183
GPX3 glutathione peroxidase 3
GSTP1 glutathione S-transferase pi 1
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IFITM3 interferon induced transmembrane protein 3
IGFBP6 insulin-like growth factor binding protein 6
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LTF lactotransferrin
MAP2K3 mitogen-activated protein kinase kinase 3
MSMO1 methylsterol monooxygenase 1
NOTCH1 notch 1
OXTR oxytocin receptor
PEA15 phosphoprotein enriched in astrocytes 15
PPP1R3C protein phosphatase 1, regulatory subunit 3C
RAD51C RAD51 paralog C
RBP1 retinol binding protein 1, cellular
RPS27L ribosomal protein S27-like
SELL selectin L
SESN1 sestrin 1
SLC16A4 solute carrier family 16, member 4
SLC39A4 solute carrier family 39 (zinc transporter), member 4
SOX9 SRY (sex determining region Y)-box 9
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRPX sushi-repeat containing protein, X-linked
TIMP1 TIMP metallopeptidase inhibitor 1
TRIM22 tripartite motif containing 22
ZMAT3 zinc finger, matrin-type 3

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ACTG2 actin, gamma 2, smooth muscle, enteric
AQP3 aquaporin 3 (Gill blood group)
ARID4B AT rich interactive domain 4B (RBP1-like)
AUTS2 autism susceptibility candidate 2
BCL6 B-cell CLL/lymphoma 6
CADM1 cell adhesion molecule 1
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CXADR coxsackie virus and adenovirus receptor
DENND1B DENN/MADD domain containing 1B
DOCK4 dedicator of cytokinesis 4
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ESR1 estrogen receptor 1
EVL Enah/Vasp-like
FAIM Fas apoptotic inhibitory molecule
FGFR2 fibroblast growth factor receptor 2
FNDC3B fibronectin type III domain containing 3B
GAB2 GRB2-associated binding protein 2
GAS1 growth arrest-specific 1
GNLY granulysin
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IGF1R insulin-like growth factor 1 receptor
ISLR immunoglobulin superfamily containing leucine-rich repeat
KAT6A K(lysine) acetyltransferase 6A
KAT6B K(lysine) acetyltransferase 6B
KRT19 keratin 19, type I
LPAR6 lysophosphatidic acid receptor 6
LPP LIM domain containing preferred translocation partner in lipoma
MTUS1 microtubule associated tumor suppressor 1
MUC16 mucin 16, cell surface associated
MUC4 mucin 4, cell surface associated
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYH11 myosin, heavy chain 11, smooth muscle
NCK1 NCK adaptor protein 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NR2F2 nuclear receptor subfamily 2, group F, member 2
PDZRN3 PDZ domain containing ring finger 3
PXDN peroxidasin
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
SETBP1 SET binding protein 1
SFRP4 secreted frizzled-related protein 4
SH3BP5 SH3-domain binding protein 5 (BTK-associated)
SHB Src homology 2 domain containing adaptor protein B
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
TACSTD2 tumor-associated calcium signal transducer 2
TUSC3 tumor suppressor candidate 3
UVRAG UV radiation resistance associated
XPO7 exportin 7
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZNF292 zinc finger protein 292
ZW10 zw10 kinetochore protein