BRD-K67090983_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

49 genes differentially expressed following the BRD-K67090983_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADIRF adipogenesis regulatory factor
ADM adrenomedullin
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C3 aldo-keto reductase family 1, member C3
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ANXA4 annexin A4
BTG1 B-cell translocation gene 1, anti-proliferative
CD24 CD24 molecule
CD36 CD36 molecule (thrombospondin receptor)
COLEC12 collectin sub-family member 12
CPA3 carboxypeptidase A3 (mast cell)
CRABP2 cellular retinoic acid binding protein 2
CYB5A cytochrome b5 type A (microsomal)
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FAM198B family with sequence similarity 198, member B
FTH1 ferritin, heavy polypeptide 1
GJA1 gap junction protein, alpha 1, 43kDa
GSE1 Gse1 coiled-coil protein
IER3 immediate early response 3
IL1B interleukin 1, beta
KDM5D lysine (K)-specific demethylase 5D
RGCC regulator of cell cycle
SRRM2 serine/arginine repetitive matrix 2
STC2 stanniocalcin 2
TPM2 tropomyosin 2 (beta)

decreased expression

Symbol Name
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKAP8 A kinase (PRKA) anchor protein 8
ASS1 argininosuccinate synthase 1
C1S complement component 1, s subcomponent
CCND2 cyclin D2
CDC34 cell division cycle 34
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
FAM57A family with sequence similarity 57, member A
GOLGA8A golgin A8 family, member A
HHEX hematopoietically expressed homeobox
LTF lactotransferrin
MAPT microtubule-associated protein tau
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
RRAGD Ras-related GTP binding D
SFRP1 secreted frizzled-related protein 1
SLPI secretory leukocyte peptidase inhibitor
WFS1 Wolfram syndrome 1 (wolframin)
ZBTB18 zinc finger and BTB domain containing 18