BRD-K67080878_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

40 genes differentially expressed following the BRD-K67080878_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALB albumin
ARMCX1 armadillo repeat containing, X-linked 1
C10ORF10 chromosome 10 open reading frame 10
CA2 carbonic anhydrase II
CAST calpastatin
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FAM69A family with sequence similarity 69, member A
GATA6 GATA binding protein 6
GSPT2 G1 to S phase transition 2
HOXD1 homeobox D1
HSPA2 heat shock 70kDa protein 2
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
RTN2 reticulon 2
S100A8 S100 calcium binding protein A8
SCGB1D2 secretoglobin, family 1D, member 2
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLAMF7 SLAM family member 7
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
THBS1 thrombospondin 1
TRIM2 tripartite motif containing 2
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
CCND1 cyclin D1
CD99 CD99 molecule
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CST3 cystatin C
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FOLR1 folate receptor 1 (adult)
HCAR3 hydroxycarboxylic acid receptor 3
KDM5D lysine (K)-specific demethylase 5D
LEF1 lymphoid enhancer-binding factor 1
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A2 S100 calcium binding protein A2
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SPRY2 sprouty homolog 2 (Drosophila)
TWIST1 twist family bHLH transcription factor 1
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)