BRD-K66847579_WZ-7043_HA1E_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

78 genes differentially expressed following the BRD-K66847579_WZ-7043_HA1E_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ATRX alpha thalassemia/mental retardation syndrome X-linked
BHLHE40 basic helix-loop-helix family, member e40
BPHL biphenyl hydrolase-like (serine hydrolase)
CCDC92 coiled-coil domain containing 92
CCL2 chemokine (C-C motif) ligand 2
CREB1 cAMP responsive element binding protein 1
DDIT4 DNA-damage-inducible transcript 4
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
EGR3 early growth response 3
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
FABP4 fatty acid binding protein 4, adipocyte
FAM69A family with sequence similarity 69, member A
FERMT2 fermitin family member 2
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGFBP3 insulin-like growth factor binding protein 3
KCNK1 potassium channel, two pore domain subfamily K, member 1
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
LAGE3 L antigen family, member 3
LMCD1 LIM and cysteine-rich domains 1
LPL lipoprotein lipase
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAOA monoamine oxidase A
MATN2 matrilin 2
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NR4A3 nuclear receptor subfamily 4, group A, member 3
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PHKA1 phosphorylase kinase, alpha 1 (muscle)
PRAME preferentially expressed antigen in melanoma
RTN2 reticulon 2
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SH3BGRL SH3 domain binding glutamate-rich protein like
THBS1 thrombospondin 1
TIMP3 TIMP metallopeptidase inhibitor 3
TM7SF2 transmembrane 7 superfamily member 2
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TTC3 tetratricopeptide repeat domain 3
TUBB2A tubulin, beta 2A class IIa
TUSC3 tumor suppressor candidate 3
ZMIZ1 zinc finger, MIZ-type containing 1

decreased expression

Symbol Name
ACSL5 acyl-CoA synthetase long-chain family member 5
ANXA1 annexin A1
APOE apolipoprotein E
CCL5 chemokine (C-C motif) ligand 5
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CFH complement factor H
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
DEPTOR DEP domain containing MTOR-interacting protein
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
DKK1 dickkopf WNT signaling pathway inhibitor 1
EFHD2 EF-hand domain family, member D2
FNBP1 formin binding protein 1
FXYD5 FXYD domain containing ion transport regulator 5
GAL galanin/GMAP prepropeptide
GATA3 GATA binding protein 3
GOLGA8A golgin A8 family, member A
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
IL13RA2 interleukin 13 receptor, alpha 2
IPO13 importin 13
LCN2 lipocalin 2
LGALS4 lectin, galactoside-binding, soluble, 4
LY75 lymphocyte antigen 75
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
NR2F1 nuclear receptor subfamily 2, group F, member 1
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
PPAP2C phosphatidic acid phosphatase type 2C
PRKCH protein kinase C, eta
PRPF4 pre-mRNA processing factor 4
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
RAB4A RAB4A, member RAS oncogene family
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
TARP TCR gamma alternate reading frame protein
TMEM30B transmembrane protein 30B
TSPAN5 tetraspanin 5
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)