BRD-K66782112_ICI-162,846_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

36 genes differentially expressed following the BRD-K66782112_ICI-162,846_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
CD24 CD24 molecule
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
DENND1B DENN/MADD domain containing 1B
DPP4 dipeptidyl-peptidase 4
DPYSL3 dihydropyrimidinase-like 3
EPAS1 endothelial PAS domain protein 1
FAM69A family with sequence similarity 69, member A
HOPX HOP homeobox
MSMB microseminoprotein, beta-
NEB nebulin
NELL2 NEL-like 2 (chicken)
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SFTPB surfactant protein B
STAP1 signal transducing adaptor family member 1
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
C6ORF48 chromosome 6 open reading frame 48
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CLEC11A C-type lectin domain family 11, member A
CST3 cystatin C
CXCL5 chemokine (C-X-C motif) ligand 5
FAM216A family with sequence similarity 216, member A
GAS7 growth arrest-specific 7
HIST1H2BK histone cluster 1, H2bk
LTBP3 latent transforming growth factor beta binding protein 3
MTF2 metal response element binding transcription factor 2
RCAN1 regulator of calcineurin 1
RYBP RING1 and YY1 binding protein
SCAND1 SCAN domain containing 1
SLC39A4 solute carrier family 39 (zinc transporter), member 4
STXBP2 syntaxin binding protein 2
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
UQCRC1 ubiquinol-cytochrome c reductase core protein I