BRD-K66426634_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

23 genes differentially expressed following the BRD-K66426634_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BASP1 brain abundant, membrane attached signal protein 1
GAS1 growth arrest-specific 1
GLRX glutaredoxin (thioltransferase)
HSPA1A heat shock 70kDa protein 1A
MAP7 microtubule-associated protein 7
MAPT microtubule-associated protein tau
PRKD3 protein kinase D3
PTK2 protein tyrosine kinase 2
SGK1 serum/glucocorticoid regulated kinase 1
SIK1 salt-inducible kinase 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC31A2 solute carrier family 31 (copper transporter), member 2
TPD52L1 tumor protein D52-like 1

decreased expression

Symbol Name
CCL20 chemokine (C-C motif) ligand 20
DEFA5 defensin, alpha 5, Paneth cell-specific
IFI6 interferon, alpha-inducible protein 6
ISG15 ISG15 ubiquitin-like modifier
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
MT1M metallothionein 1M
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
SFTPB surfactant protein B