BRD-K66296774_-666_NPC_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

67 genes differentially expressed following the BRD-K66296774_-666_NPC_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACLY ATP citrate lyase
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AQP3 aquaporin 3 (Gill blood group)
BTG1 B-cell translocation gene 1, anti-proliferative
CD24 CD24 molecule
CFB complement factor B
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
EBP emopamil binding protein (sterol isomerase)
ELOVL6 ELOVL fatty acid elongase 6
EPHA3 EPH receptor A3
FADS1 fatty acid desaturase 1
FADS2 fatty acid desaturase 2
FASN fatty acid synthase
FDPS farnesyl diphosphate synthase
FGA fibrinogen alpha chain
FGG fibrinogen gamma chain
FXYD2 FXYD domain containing ion transport regulator 2
GLA galactosidase, alpha
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
ICAM1 intercellular adhesion molecule 1
INSIG1 insulin induced gene 1
LYST lysosomal trafficking regulator
NSDHL NAD(P) dependent steroid dehydrogenase-like
NTS neurotensin
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
S100P S100 calcium binding protein P
SAT1 spermidine/spermine N1-acetyltransferase 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SPRR1B small proline-rich protein 1B
SSR4 signal sequence receptor, delta
TM4SF4 transmembrane 4 L six family member 4
TM7SF2 transmembrane 7 superfamily member 2
TMEM97 transmembrane protein 97
TOX3 TOX high mobility group box family member 3
TUBB2A tubulin, beta 2A class IIa
ZBTB18 zinc finger and BTB domain containing 18

decreased expression

Symbol Name
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ANXA3 annexin A3
ANXA6 annexin A6
CADM1 cell adhesion molecule 1
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLIC5 chloride intracellular channel 5
COL3A1 collagen, type III, alpha 1
CSRP1 cysteine and glycine-rich protein 1
CYR61 cysteine-rich, angiogenic inducer, 61
DLC1 DLC1 Rho GTPase activating protein
FCGBP Fc fragment of IgG binding protein
GATA6 GATA binding protein 6
GBP1 guanylate binding protein 1, interferon-inducible
GSTM3 glutathione S-transferase mu 3 (brain)
HBB hemoglobin, beta
IFI27 interferon, alpha-inducible protein 27
IGFBP4 insulin-like growth factor binding protein 4
KRT19 keratin 19, type I
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYL9 myosin, light chain 9, regulatory
PALLD palladin, cytoskeletal associated protein
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
RND3 Rho family GTPase 3
SELENBP1 selenium binding protein 1
TAGLN transgelin
TOP2A topoisomerase (DNA) II alpha 170kDa
TTC39A tetratricopeptide repeat domain 39A