BRD-K66198023_losartan_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

38 genes differentially expressed following the BRD-K66198023_losartan_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALB albumin
ANPEP alanyl (membrane) aminopeptidase
APOA2 apolipoprotein A-II
AQP3 aquaporin 3 (Gill blood group)
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
FCGBP Fc fragment of IgG binding protein
HLA-DRA major histocompatibility complex, class II, DR alpha
MMP1 matrix metallopeptidase 1
MOK MOK protein kinase
RAP1GAP RAP1 GTPase activating protein
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
TNC tenascin C
TUBB2A tubulin, beta 2A class IIa
TUSC3 tumor suppressor candidate 3
ZNF395 zinc finger protein 395

decreased expression

Symbol Name
AGR2 anterior gradient 2
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ANOS1 anosmin 1
DCN decorin
DYNLT3 dynein, light chain, Tctex-type 3
EGFR epidermal growth factor receptor
IGFBP3 insulin-like growth factor binding protein 3
LUM lumican
MET MET proto-oncogene, receptor tyrosine kinase
MID1 midline 1
MMP7 matrix metallopeptidase 7
NR1D2 nuclear receptor subfamily 1, group D, member 2
OLFM4 olfactomedin 4
PALLD palladin, cytoskeletal associated protein
PLBD1 phospholipase B domain containing 1
RGS2 regulator of G-protein signaling 2
SFRP4 secreted frizzled-related protein 4
SMAD7 SMAD family member 7
SOX9 SRY (sex determining region Y)-box 9
TMEM176B transmembrane protein 176B