BRD-K65904652_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

51 genes differentially expressed following the BRD-K65904652_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADM adrenomedullin
ALDOC aldolase C, fructose-bisphosphate
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CFD complement factor D (adipsin)
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CSRP1 cysteine and glycine-rich protein 1
DDIT4 DNA-damage-inducible transcript 4
ECM1 extracellular matrix protein 1
FOXO4 forkhead box O4
GAS1 growth arrest-specific 1
GLRX glutaredoxin (thioltransferase)
GOLM1 golgi membrane protein 1
HEPH hephaestin
IFI27 interferon, alpha-inducible protein 27
IGFBP5 insulin-like growth factor binding protein 5
MKNK2 MAP kinase interacting serine/threonine kinase 2
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
NDRG1 N-myc downstream regulated 1
NELL2 NEL-like 2 (chicken)
PAM peptidylglycine alpha-amidating monooxygenase
PFKM phosphofructokinase, muscle
PGM1 phosphoglucomutase 1
PLIN2 perilipin 2
PPAP2A phosphatidic acid phosphatase type 2A
PYGL phosphorylase, glycogen, liver
RHOBTB3 Rho-related BTB domain containing 3
SAT1 spermidine/spermine N1-acetyltransferase 1
SERINC5 serine incorporator 5
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFRP1 secreted frizzled-related protein 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
STC1 stanniocalcin 1
SYT1 synaptotagmin I
TGFBI transforming growth factor, beta-induced, 68kDa
TMSB15A thymosin beta 15a
TXNIP thioredoxin interacting protein
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
ADI1 acireductone dioxygenase 1
ALCAM activated leukocyte cell adhesion molecule
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
ICAM3 intercellular adhesion molecule 3
ODC1 ornithine decarboxylase 1
PDGFA platelet-derived growth factor alpha polypeptide
PPIF peptidylprolyl isomerase F
S100A2 S100 calcium binding protein A2
SCAND1 SCAN domain containing 1