BRD-K65904652_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

85 genes differentially expressed following the BRD-K65904652_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAM19 ADAM metallopeptidase domain 19
AIM1 absent in melanoma 1
ALCAM activated leukocyte cell adhesion molecule
AMIGO2 adhesion molecule with Ig-like domain 2
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
CFD complement factor D (adipsin)
CSRP2 cysteine and glycine-rich protein 2
DEFB1 defensin, beta 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
F2R coagulation factor II (thrombin) receptor
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
IDS iduronate 2-sulfatase
IFITM1 interferon induced transmembrane protein 1
IFITM2 interferon induced transmembrane protein 2
IGFBP1 insulin-like growth factor binding protein 1
LEPR leptin receptor
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LRP4 low density lipoprotein receptor-related protein 4
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MAPT microtubule-associated protein tau
MT1X metallothionein 1X
MT2A metallothionein 2A
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NPEPL1 aminopeptidase-like 1
NRN1 neuritin 1
OAT ornithine aminotransferase
PEG10 paternally expressed 10
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLA1A phospholipase A1 member A
PLAC8 placenta-specific 8
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PNMAL1 paraneoplastic Ma antigen family-like 1
PRAME preferentially expressed antigen in melanoma
PRKCQ protein kinase C, theta
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RHOB ras homolog family member B
S100A10 S100 calcium binding protein A10
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SMCO4 single-pass membrane protein with coiled-coil domains 4
SOX4 SRY (sex determining region Y)-box 4
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRGN serglycin
TLR4 toll-like receptor 4
XBP1 X-box binding protein 1

decreased expression

Symbol Name
ADAM28 ADAM metallopeptidase domain 28
BCL7B B-cell CLL/lymphoma 7B
CCDC109B coiled-coil domain containing 109B
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CHGB chromogranin B
CLDN10 claudin 10
CNPY3 canopy FGF signaling regulator 3
COL10A1 collagen, type X, alpha 1
CPE carboxypeptidase E
DLK1 delta-like 1 homolog (Drosophila)
FGFR3 fibroblast growth factor receptor 3
FMO1 flavin containing monooxygenase 1
GAL galanin/GMAP prepropeptide
HIST1H4C histone cluster 1, H4c
IFRD2 interferon-related developmental regulator 2
LRMP lymphoid-restricted membrane protein
MARCH3 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase
MEF2C myocyte enhancer factor 2C
MUC16 mucin 16, cell surface associated
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
PAEP progestagen-associated endometrial protein
PCSK1 proprotein convertase subtilisin/kexin type 1
PGBD5 piggyBac transposable element derived 5
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
S100P S100 calcium binding protein P
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SFRP4 secreted frizzled-related protein 4
SOCS2 suppressor of cytokine signaling 2
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
TCF4 transcription factor 4
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TSPAN12 tetraspanin 12
VCAM1 vascular cell adhesion molecule 1
VDAC1 voltage-dependent anion channel 1
XYLT1 xylosyltransferase I