BRD-K65404805_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

35 genes differentially expressed following the BRD-K65404805_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
AGR2 anterior gradient 2
AKR1C3 aldo-keto reductase family 1, member C3
ANXA1 annexin A1
ARHGAP29 Rho GTPase activating protein 29
BLVRA biliverdin reductase A
CD302 CD302 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CHRDL1 chordin-like 1
DEGS1 delta(4)-desaturase, sphingolipid 1
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
ETV5 ets variant 5
FADS1 fatty acid desaturase 1
GDF15 growth differentiation factor 15
GPC3 glypican 3
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
INSIG1 insulin induced gene 1
IRS2 insulin receptor substrate 2
LEF1 lymphoid enhancer-binding factor 1
LYZ lysozyme
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SFTPA2 surfactant protein A2
SYBU syntabulin (syntaxin-interacting)
TFF3 trefoil factor 3 (intestinal)
TMEM100 transmembrane protein 100
TNNT1 troponin T type 1 (skeletal, slow)
TSPAN4 tetraspanin 4
TSPAN8 tetraspanin 8

decreased expression

Symbol Name
CDK7 cyclin-dependent kinase 7
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
FOSL1 FOS-like antigen 1
MAN2A1 mannosidase, alpha, class 2A, member 1
MAP7 microtubule-associated protein 7
SENP6 SUMO1/sentrin specific peptidase 6