BRD-K65242613_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

68 genes differentially expressed following the BRD-K65242613_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
AMDHD2 amidohydrolase domain containing 2
ANXA1 annexin A1
APOD apolipoprotein D
ASS1 argininosuccinate synthase 1
CD3D CD3d molecule, delta (CD3-TCR complex)
COL9A3 collagen, type IX, alpha 3
CRYAB crystallin, alpha B
DDIT4 DNA-damage-inducible transcript 4
DDR1 discoidin domain receptor tyrosine kinase 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EPB41L3 erythrocyte membrane protein band 4.1-like 3
F12 coagulation factor XII (Hageman factor)
FCGBP Fc fragment of IgG binding protein
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
FYN FYN proto-oncogene, Src family tyrosine kinase
GOLGA8A golgin A8 family, member A
GRN granulin
GSN gelsolin
IER3 immediate early response 3
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL7R interleukin 7 receptor
ITK IL2-inducible T-cell kinase
LAPTM4B lysosomal protein transmembrane 4 beta
LCN2 lipocalin 2
LEF1 lymphoid enhancer-binding factor 1
MMD monocyte to macrophage differentiation-associated
MT1X metallothionein 1X
NPTX2 neuronal pentraxin II
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PER1 period circadian clock 1
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SORBS1 sorbin and SH3 domain containing 1
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
TGFBI transforming growth factor, beta-induced, 68kDa
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZIC1 Zic family member 1

decreased expression

Symbol Name
ACP5 acid phosphatase 5, tartrate resistant
ACTA2 actin, alpha 2, smooth muscle, aorta
ANKRD10 ankyrin repeat domain 10
ATF5 activating transcription factor 5
BEX1 brain expressed, X-linked 1
CD24 CD24 molecule
CPB1 carboxypeptidase B1 (tissue)
CPE carboxypeptidase E
DAPK1 death-associated protein kinase 1
E2F2 E2F transcription factor 2
FAM46A family with sequence similarity 46, member A
FOS FBJ murine osteosarcoma viral oncogene homolog
FXYD3 FXYD domain containing ion transport regulator 3
GPNMB glycoprotein (transmembrane) nmb
IL1RN interleukin 1 receptor antagonist
KIAA0907 KIAA0907
MAP7 microtubule-associated protein 7
MMP12 matrix metallopeptidase 12
MMP9 matrix metallopeptidase 9
NCF2 neutrophil cytosolic factor 2
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma
S100A8 S100 calcium binding protein A8
SFTPC surfactant protein C
TACSTD2 tumor-associated calcium signal transducer 2
TAGLN transgelin
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
YME1L1 YME1-like 1 ATPase