BRD-K65182930_NVP-AUY922_MDAMB231_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

55 genes differentially expressed following the BRD-K65182930_NVP-AUY922_MDAMB231_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
APOE apolipoprotein E
BAG3 BCL2-associated athanogene 3
BCL2A1 BCL2-related protein A1
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
E2F2 E2F transcription factor 2
EAPP E2F-associated phosphoprotein
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
FSD1 fibronectin type III and SPRY domain containing 1
GATA3 GATA binding protein 3
GRWD1 glutamate-rich WD repeat containing 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPB1 heat shock 27kDa protein 1
HSPH1 heat shock 105kDa/110kDa protein 1
KRT19 keratin 19, type I
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PRKCQ protein kinase C, theta
RRAS2 related RAS viral (r-ras) oncogene homolog 2
SGK1 serum/glucocorticoid regulated kinase 1
TMEM14A transmembrane protein 14A

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
BHLHE41 basic helix-loop-helix family, member e41
BLNK B-cell linker
CD99 CD99 molecule
CREB1 cAMP responsive element binding protein 1
DCN decorin
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
EREG epiregulin
FRZB frizzled-related protein
GPM6A glycoprotein M6A
GPM6B glycoprotein M6B
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
GUSBP3 glucuronidase, beta pseudogene 3
HBB hemoglobin, beta
IER3 immediate early response 3
KRT13 keratin 13, type I
KRT81 keratin 81, type II
KYNU kynureninase
MALL mal, T-cell differentiation protein-like
MAN1A1 mannosidase, alpha, class 1A, member 1
MAP7 microtubule-associated protein 7
NRN1 neuritin 1
PCSK1 proprotein convertase subtilisin/kexin type 1
PRR15L proline rich 15-like
PTN pleiotrophin
REEP1 receptor accessory protein 1
RNASE4 ribonuclease, RNase A family, 4
SDC1 syndecan 1
SMC1A structural maintenance of chromosomes 1A
SORBS2 sorbin and SH3 domain containing 2
VCL vinculin