BRD-K65182930_NVP-AUY922_HS578T_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

64 genes differentially expressed following the BRD-K65182930_NVP-AUY922_HS578T_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ASNS asparagine synthetase (glutamine-hydrolyzing)
BAG3 BCL2-associated athanogene 3
BPGM 2,3-bisphosphoglycerate mutase
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLU clusterin
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPH1 heat shock 105kDa/110kDa protein 1
IGHD immunoglobulin heavy constant delta
IGKV3-20 immunoglobulin kappa variable 3-20
KDM5D lysine (K)-specific demethylase 5D
KRT7 keratin 7, type II
LEF1 lymphoid enhancer-binding factor 1
MAGEA1 melanoma antigen family A1
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MMP10 matrix metallopeptidase 10
MUC5B mucin 5B, oligomeric mucus/gel-forming
PENK proenkephalin
PIR pirin (iron-binding nuclear protein)
RGS2 regulator of G-protein signaling 2
RGS4 regulator of G-protein signaling 4
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPP1 secreted phosphoprotein 1
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPD52L1 tumor protein D52-like 1

decreased expression

Symbol Name
ANGPTL2 angiopoietin-like 2
AREG amphiregulin
CD24 CD24 molecule
CD36 CD36 molecule (thrombospondin receptor)
CLC Charcot-Leyden crystal galectin
CPE carboxypeptidase E
FABP4 fatty acid binding protein 4, adipocyte
FHL1 four and a half LIM domains 1
FZD7 frizzled class receptor 7
GREM1 gremlin 1, DAN family BMP antagonist
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IER3 immediate early response 3
IFI6 interferon, alpha-inducible protein 6
IGF1 insulin-like growth factor 1 (somatomedin C)
MEIS2 Meis homeobox 2
NT5E 5'-nucleotidase, ecto (CD73)
PEG10 paternally expressed 10
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
SDC4 syndecan 4
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)