BRD-K65182930_NVP-AUY922_HEPG2_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

229 genes differentially expressed following the BRD-K65182930_NVP-AUY922_HEPG2_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACPP acid phosphatase, prostate
ACSL3 acyl-CoA synthetase long-chain family member 3
ADCK3 aarF domain containing kinase 3
ADD3 adducin 3 (gamma)
AKAP8L A kinase (PRKA) anchor protein 8-like
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ALCAM activated leukocyte cell adhesion molecule
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
ASMTL acetylserotonin O-methyltransferase-like
ATF3 activating transcription factor 3
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP9A ATPase, class II, type 9A
BAG3 BCL2-associated athanogene 3
BBX bobby sox homolog (Drosophila)
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BTN3A2 butyrophilin, subfamily 3, member A2
CBR3 carbonyl reductase 3
CCNG2 cyclin G2
CD59 CD59 molecule, complement regulatory protein
CFH complement factor H
CHPT1 choline phosphotransferase 1
CLDN5 claudin 5
CLU clusterin
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CXCL13 chemokine (C-X-C motif) ligand 13
CYB561 cytochrome b561
CYLD cylindromatosis (turban tumor syndrome)
CYTH1 cytohesin 1
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DHRS9 dehydrogenase/reductase (SDR family) member 9
DUSP14 dual specificity phosphatase 14
ERP44 endoplasmic reticulum protein 44
FBXO11 F-box protein 11
FBXO7 F-box protein 7
FNBP1 formin binding protein 1
FXR1 fragile X mental retardation, autosomal homolog 1
GADD45B growth arrest and DNA-damage-inducible, beta
GLG1 golgi glycoprotein 1
GLUL glutamate-ammonia ligase
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GOLM1 golgi membrane protein 1
GPRC5B G protein-coupled receptor, class C, group 5, member B
GPX3 glutathione peroxidase 3
HECA headcase homolog (Drosophila)
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA1A heat shock 70kDa protein 1A
HSPA8 heat shock 70kDa protein 8
HSPB1 heat shock 27kDa protein 1
IDS iduronate 2-sulfatase
IFRD1 interferon-related developmental regulator 1
IL7R interleukin 7 receptor
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
ITGB6 integrin, beta 6
KIAA0368 KIAA0368
KLHDC10 kelch domain containing 10
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MT1M metallothionein 1M
MXD4 MAX dimerization protein 4
MYO10 myosin X
MYO5A myosin VA (heavy chain 12, myoxin)
NCOA3 nuclear receptor coactivator 3
NEFH neurofilament, heavy polypeptide
NRIP1 nuclear receptor interacting protein 1
OLFM4 olfactomedin 4
OSBPL2 oxysterol binding protein-like 2
OSBPL9 oxysterol binding protein-like 9
OSER1 oxidative stress responsive serine-rich 1
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PHACTR2 phosphatase and actin regulator 2
PI3 peptidase inhibitor 3, skin-derived
POR P450 (cytochrome) oxidoreductase
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAP2A RAP2A, member of RAS oncogene family
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RGS10 regulator of G-protein signaling 10
RUNX3 runt-related transcription factor 3
RYBP RING1 and YY1 binding protein
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC26A3 solute carrier family 26 (anion exchanger), member 3
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SRGN serglycin
TARP TCR gamma alternate reading frame protein
TBC1D15 TBC1 domain family, member 15
TBC1D4 TBC1 domain family, member 4
TTC3 tetratricopeptide repeat domain 3
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
UBXN7 UBX domain protein 7
UGCG UDP-glucose ceramide glucosyltransferase
UGDH UDP-glucose 6-dehydrogenase
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
YPEL5 yippee-like 5 (Drosophila)
ZDHHC7 zinc finger, DHHC-type containing 7

decreased expression

Symbol Name
ABLIM1 actin binding LIM protein 1
ACTG2 actin, gamma 2, smooth muscle, enteric
AHNAK2 AHNAK nucleoprotein 2
AKAP12 A kinase (PRKA) anchor protein 12
ALG6 ALG6, alpha-1,3-glucosyltransferase
ALOX5 arachidonate 5-lipoxygenase
AMDHD2 amidohydrolase domain containing 2
ANKRD10 ankyrin repeat domain 10
ANKRD36B ankyrin repeat domain 36B
BAZ1A bromodomain adjacent to zinc finger domain, 1A
C2CD5 C2 calcium-dependent domain containing 5
C3 complement component 3
CADM1 cell adhesion molecule 1
CD24 CD24 molecule
CD3EAP CD3e molecule, epsilon associated protein
CD44 CD44 molecule (Indian blood group)
CDC20 cell division cycle 20
CDC7 cell division cycle 7
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CKLF chemokine-like factor
COA3 cytochrome c oxidase assembly factor 3
COL11A1 collagen, type XI, alpha 1
COL1A1 collagen, type I, alpha 1
CSTA cystatin A (stefin A)
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL14 chemokine (C-X-C motif) ligand 14
DCN decorin
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DESI1 desumoylating isopeptidase 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DPH2 DPH2 homolog (S. cerevisiae)
DPYSL3 dihydropyrimidinase-like 3
DUSP6 dual specificity phosphatase 6
EMG1 EMG1 N1-specific pseudouridine methyltransferase
ESR1 estrogen receptor 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM216A family with sequence similarity 216, member A
FARSA phenylalanyl-tRNA synthetase, alpha subunit
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FRZB frizzled-related protein
GALE UDP-galactose-4-epimerase
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GINS1 GINS complex subunit 1 (Psf1 homolog)
GLRX glutaredoxin (thioltransferase)
GPX1 glutathione peroxidase 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IER3 immediate early response 3
IFRD2 interferon-related developmental regulator 2
IGFBP6 insulin-like growth factor binding protein 6
IL32 interleukin 32
INHBA inhibin, beta A
IPO4 importin 4
KCTD12 potassium channel tetramerization domain containing 12
KRT19 keratin 19, type I
LGALS3 lectin, galactoside-binding, soluble, 3
LMCD1 LIM and cysteine-rich domains 1
LOC100505650 uncharacterized LOC100505650
LUM lumican
MAN1A1 mannosidase, alpha, class 1A, member 1
MARCKSL1 MARCKS-like 1
MFAP5 microfibrillar associated protein 5
MPZL2 myelin protein zero-like 2
MRPL12 mitochondrial ribosomal protein L12
MRPL57 mitochondrial ribosomal protein L57
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MSLN mesothelin
MX2 MX dynamin-like GTPase 2
MYO1B myosin IB
NDUFAF3 NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
NEFL neurofilament, light polypeptide
NHP2 NHP2 ribonucleoprotein
NME1 NME/NM23 nucleoside diphosphate kinase 1
NT5E 5'-nucleotidase, ecto (CD73)
NUTF2 nuclear transport factor 2
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2
OSBPL10 oxysterol binding protein-like 10
OXLD1 oxidoreductase-like domain containing 1
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
PCSK1 proprotein convertase subtilisin/kexin type 1
PDZRN3 PDZ domain containing ring finger 3
PFKP phosphofructokinase, platelet
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLN phospholamban
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
PNP purine nucleoside phosphorylase
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma
PRDX2 peroxiredoxin 2
PREB prolactin regulatory element binding
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PTGIS prostaglandin I2 (prostacyclin) synthase
PTP4A1 protein tyrosine phosphatase type IVA, member 1
PYCR1 pyrroline-5-carboxylate reductase 1
RBBP8 retinoblastoma binding protein 8
RHOB ras homolog family member B
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
RRM2 ribonucleotide reductase M2
S100A2 S100 calcium binding protein A2
SCN3A sodium channel, voltage gated, type III alpha subunit
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFRP1 secreted frizzled-related protein 1
SFRP4 secreted frizzled-related protein 4
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SNX10 sorting nexin 10
SOX4 SRY (sex determining region Y)-box 4
SPTSSA serine palmitoyltransferase, small subunit A
SRM spermidine synthase
SRSF6 serine/arginine-rich splicing factor 6
STRA13 stimulated by retinoic acid 13
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
TAGLN transgelin
THTPA thiamine triphosphatase
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMEM5 transmembrane protein 5
TYMP thymidine phosphorylase
TYMS thymidylate synthetase
UBE3C ubiquitin protein ligase E3C
VCAN versican
XBP1 X-box binding protein 1
ZNF593 zinc finger protein 593
ZWINT ZW10 interacting kinetochore protein