BRD-K65182930_NVP-AUY922_BT20_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

69 genes differentially expressed following the BRD-K65182930_NVP-AUY922_BT20_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGR2 anterior gradient 2
ARMCX3 armadillo repeat containing, X-linked 3
BAG3 BCL2-associated athanogene 3
BHLHE41 basic helix-loop-helix family, member e41
BIRC3 baculoviral IAP repeat containing 3
C3 complement component 3
C4BPA complement component 4 binding protein, alpha
CDK2AP2 cyclin-dependent kinase 2 associated protein 2
CLDN10 claudin 10
COL9A3 collagen, type IX, alpha 3
CRISP3 cysteine-rich secretory protein 3
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT3 DNA-damage-inducible transcript 3
DEFB1 defensin, beta 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
FKBP11 FK506 binding protein 11, 19 kDa
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA1A heat shock 70kDa protein 1A
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPH1 heat shock 105kDa/110kDa protein 1
HYOU1 hypoxia up-regulated 1
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV3-20 immunoglobulin kappa variable 3-20
IGKV4-1 immunoglobulin kappa variable 4-1
IGLV1-40 immunoglobulin lambda variable 1-40
IGLV2-23 immunoglobulin lambda variable 2-23
ITM2A integral membrane protein 2A
KRT17 keratin 17, type I
LYZ lysozyme
MANF mesencephalic astrocyte-derived neurotrophic factor
MUC16 mucin 16, cell surface associated
MUC5B mucin 5B, oligomeric mucus/gel-forming
PDIA4 protein disulfide isomerase family A, member 4
POU2AF1 POU class 2 associating factor 1
PPIB peptidylprolyl isomerase B (cyclophilin B)
RAD9A RAD9 homolog A (S. pombe)
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RUNX3 runt-related transcription factor 3
SLPI secretory leukocyte peptidase inhibitor
TACSTD2 tumor-associated calcium signal transducer 2
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TGM2 transglutaminase 2
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
XBP1 X-box binding protein 1

decreased expression

Symbol Name
AREG amphiregulin
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CRABP2 cellular retinoic acid binding protein 2
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DSP desmoplakin
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
HMGB3 high mobility group box 3
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial
IL13RA2 interleukin 13 receptor, alpha 2
PCP4 Purkinje cell protein 4
POSTN periostin, osteoblast specific factor
PSD3 pleckstrin and Sec7 domain containing 3
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SULF1 sulfatase 1