BRD-K65182930_NVP-AUY922_BT20_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

37 genes differentially expressed following the BRD-K65182930_NVP-AUY922_BT20_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BAG3 BCL2-associated athanogene 3
CCL4 chemokine (C-C motif) ligand 4
CCL5 chemokine (C-C motif) ligand 5
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP2 dual specificity phosphatase 2
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GNLY granulysin
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPB8 heat shock 22kDa protein 8
IER5 immediate early response 5
IL2RB interleukin 2 receptor, beta
KRT19 keratin 19, type I
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like
MMP7 matrix metallopeptidase 7
NKG7 natural killer cell granule protein 7
PDE4B phosphodiesterase 4B, cAMP-specific
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RGS1 regulator of G-protein signaling 1
RUNX3 runt-related transcription factor 3
S100P S100 calcium binding protein P
SIK1 salt-inducible kinase 1
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
XCL1 chemokine (C motif) ligand 1

decreased expression

Symbol Name
CHIC2 cysteine-rich hydrophobic domain 2
FABP4 fatty acid binding protein 4, adipocyte
FST follistatin
NREP neuronal regeneration related protein
SDC2 syndecan 2
SEPP1 selenoprotein P, plasma, 1
SPP1 secreted phosphoprotein 1