BRD-K65182930_NVP-AUY922_BT20_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

161 genes differentially expressed following the BRD-K65182930_NVP-AUY922_BT20_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRG2 adhesion G protein-coupled receptor G2
AFF1 AF4/FMR2 family, member 1
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
AURKA aurora kinase A
BAG3 BCL2-associated athanogene 3
BEX1 brain expressed, X-linked 1
BID BH3 interacting domain death agonist
BIRC3 baculoviral IAP repeat containing 3
CALU calumenin
CAPN6 calpain 6
CCL20 chemokine (C-C motif) ligand 20
CCNG1 cyclin G1
CD3D CD3d molecule, delta (CD3-TCR complex)
CDK19 cyclin-dependent kinase 19
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLU clusterin
CPVL carboxypeptidase, vitellogenic-like
CXCL8 chemokine (C-X-C motif) ligand 8
DEFB1 defensin, beta 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPHA4 EPH receptor A4
ESR1 estrogen receptor 1
FAM117A family with sequence similarity 117, member A
FAM65B family with sequence similarity 65, member B
FXR1 fragile X mental retardation, autosomal homolog 1
GAS1 growth arrest-specific 1
GLIPR1 GLI pathogenesis-related 1
GLUL glutamate-ammonia ligase
GPC3 glypican 3
GPNMB glycoprotein (transmembrane) nmb
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HOXA10 homeobox A10
HSPA1A heat shock 70kDa protein 1A
HSPA4L heat shock 70kDa protein 4-like
HSPA8 heat shock 70kDa protein 8
HSPB8 heat shock 22kDa protein 8
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IGFBP1 insulin-like growth factor binding protein 1
IGFBP3 insulin-like growth factor binding protein 3
JMJD6 jumonji domain containing 6
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KLHDC10 kelch domain containing 10
KRT19 keratin 19, type I
LOX lysyl oxidase
LTB lymphotoxin beta (TNF superfamily, member 3)
MAGED1 melanoma antigen family D1
MAL mal, T-cell differentiation protein
NEFL neurofilament, light polypeptide
NEFM neurofilament, medium polypeptide
NPTX2 neuronal pentraxin II
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PBK PDZ binding kinase
PCP4 Purkinje cell protein 4
PNMAL1 paraneoplastic Ma antigen family-like 1
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTN pleiotrophin
PTPRC protein tyrosine phosphatase, receptor type, C
QPRT quinolinate phosphoribosyltransferase
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RGS4 regulator of G-protein signaling 4
SCAF11 SR-related CTD-associated factor 11
SEC31A SEC31 homolog A (S. cerevisiae)
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SRGN serglycin
STK26 serine/threonine protein kinase 26
UBFD1 ubiquitin family domain containing 1
WFDC2 WAP four-disulfide core domain 2

decreased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ACKR3 atypical chemokine receptor 3
ADGRF5 adhesion G protein-coupled receptor F5
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
AMIGO2 adhesion molecule with Ig-like domain 2
ANXA1 annexin A1
ANXA3 annexin A3
AREG amphiregulin
ATF3 activating transcription factor 3
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CCND2 cyclin D2
CD24 CD24 molecule
CD36 CD36 molecule (thrombospondin receptor)
CDC45 cell division cycle 45
CLC Charcot-Leyden crystal galectin
CRIP2 cysteine-rich protein 2
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DYNLT1 dynein, light chain, Tctex-type 1
EBP emopamil binding protein (sterol isomerase)
ECHDC3 enoyl CoA hydratase domain containing 3
EIF5A eukaryotic translation initiation factor 5A
EMP1 epithelial membrane protein 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
F3 coagulation factor III (thromboplastin, tissue factor)
FABP4 fatty acid binding protein 4, adipocyte
FILIP1L filamin A interacting protein 1-like
FJX1 four jointed box 1 (Drosophila)
FN1 fibronectin 1
FOSL1 FOS-like antigen 1
FXYD5 FXYD domain containing ion transport regulator 5
G0S2 G0/G1 switch 2
GADD45A growth arrest and DNA-damage-inducible, alpha
GALE UDP-galactose-4-epimerase
H1F0 H1 histone family, member 0
HACD1 3-hydroxyacyl-CoA dehydratase 1
HBEGF heparin-binding EGF-like growth factor
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
HMOX1 heme oxygenase 1
HOPX HOP homeobox
IER3 immediate early response 3
IGHD immunoglobulin heavy constant delta
INHBA inhibin, beta A
ITGA6 integrin, alpha 6
LDLR low density lipoprotein receptor
LEPROT leptin receptor overlapping transcript
LIMCH1 LIM and calponin homology domains 1
LMCD1 LIM and cysteine-rich domains 1
LPL lipoprotein lipase
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAPK13 mitogen-activated protein kinase 13
MARCKSL1 MARCKS-like 1
MBNL2 muscleblind-like splicing regulator 2
MCM4 minichromosome maintenance complex component 4
MCM5 minichromosome maintenance complex component 5
MCM6 minichromosome maintenance complex component 6
MMD monocyte to macrophage differentiation-associated
MPHOSPH6 M-phase phosphoprotein 6
MPO myeloperoxidase
MUC1 mucin 1, cell surface associated
NFIB nuclear factor I/B
NRIP1 nuclear receptor interacting protein 1
NRP1 neuropilin 1
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PCNA proliferating cell nuclear antigen
PEA15 phosphoprotein enriched in astrocytes 15
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PLAU plasminogen activator, urokinase
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PNP purine nucleoside phosphorylase
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PRKCD protein kinase C, delta
PSMG1 proteasome (prosome, macropain) assembly chaperone 1
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RAB13 RAB13, member RAS oncogene family
RIN2 Ras and Rab interactor 2
S100A9 S100 calcium binding protein A9
SDC1 syndecan 1
SFN stratifin
SLC39A4 solute carrier family 39 (zinc transporter), member 4
SPON1 spondin 1, extracellular matrix protein
STEAP3 STEAP family member 3, metalloreductase
TGFBI transforming growth factor, beta-induced, 68kDa
THBS1 thrombospondin 1
TKTL1 transketolase-like 1
TM4SF1 transmembrane 4 L six family member 1
TPM1 tropomyosin 1 (alpha)
VCAN versican
WNT5A wingless-type MMTV integration site family, member 5A
ZFPM2 zinc finger protein, FOG family member 2