BRD-K65182930_NVP-AUY922_BT20_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

96 genes differentially expressed following the BRD-K65182930_NVP-AUY922_BT20_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AURKA aurora kinase A
BCL2A1 BCL2-related protein A1
CA12 carbonic anhydrase XII
CCDC28A coiled-coil domain containing 28A
CDK19 cyclin-dependent kinase 19
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CIT citron rho-interacting serine/threonine kinase
CKS2 CDC28 protein kinase regulatory subunit 2
COL2A1 collagen, type II, alpha 1
COL3A1 collagen, type III, alpha 1
CXCL8 chemokine (C-X-C motif) ligand 8
DUSP2 dual specificity phosphatase 2
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
GPC3 glypican 3
GPNMB glycoprotein (transmembrane) nmb
HSPA1A heat shock 70kDa protein 1A
HSPA8 heat shock 70kDa protein 8
IGKV4-1 immunoglobulin kappa variable 4-1
JMJD6 jumonji domain containing 6
LAMC1 laminin, gamma 1 (formerly LAMB2)
LRBA LPS-responsive vesicle trafficking, beach and anchor containing
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
NEBL nebulette
OXTR oxytocin receptor
PRDX6 peroxiredoxin 6
PTN pleiotrophin
RAB21 RAB21, member RAS oncogene family
SELENBP1 selenium binding protein 1
SEPP1 selenoprotein P, plasma, 1
SLC16A4 solute carrier family 16, member 4
SMAD3 SMAD family member 3
SOD1 superoxide dismutase 1, soluble
TNS1 tensin 1
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
UGCG UDP-glucose ceramide glucosyltransferase

decreased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ACD adrenocortical dysplasia homolog (mouse)
ACTN1 actinin, alpha 1
AKAP12 A kinase (PRKA) anchor protein 12
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AMIGO2 adhesion molecule with Ig-like domain 2
ANPEP alanyl (membrane) aminopeptidase
ANXA1 annexin A1
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CAPN2 calpain 2, (m/II) large subunit
CD24 CD24 molecule
CD302 CD302 molecule
CDC45 cell division cycle 45
CFD complement factor D (adipsin)
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CLC Charcot-Leyden crystal galectin
CYR61 cysteine-rich, angiogenic inducer, 61
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
EIF5A eukaryotic translation initiation factor 5A
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FOSL1 FOS-like antigen 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GFOD1 glucose-fructose oxidoreductase domain containing 1
GINS2 GINS complex subunit 2 (Psf2 homolog)
HELLS helicase, lymphoid-specific
HHEX hematopoietically expressed homeobox
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HOMER3 homer scaffolding protein 3
IER3 immediate early response 3
INHBA inhibin, beta A
IRAK1 interleukin-1 receptor-associated kinase 1
KRT23 keratin 23, type I
LYZ lysozyme
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MTSS1 metastasis suppressor 1
NFIB nuclear factor I/B
NQO2 NAD(P)H dehydrogenase, quinone 2
NRIP1 nuclear receptor interacting protein 1
NRP1 neuropilin 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLK2 polo-like kinase 2
PNP purine nucleoside phosphorylase
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PRIM1 primase, DNA, polypeptide 1 (49kDa)
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
S100A11 S100 calcium binding protein A11
SCAND1 SCAN domain containing 1
SFN stratifin
SNAI2 snail family zinc finger 2
TFPI2 tissue factor pathway inhibitor 2
THBS1 thrombospondin 1
TOR1A torsin family 1, member A (torsin A)
TPM1 tropomyosin 1 (alpha)
TSPAN4 tetraspanin 4
VCAN versican
WNT5A wingless-type MMTV integration site family, member 5A
ZFPM2 zinc finger protein, FOG family member 2