BRD-K64890080_BI-2536_SKBR3_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

67 genes differentially expressed following the BRD-K64890080_BI-2536_SKBR3_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
CCNE2 cyclin E2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CPM carboxypeptidase M
CTSC cathepsin C
ETV1 ets variant 1
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GDF15 growth differentiation factor 15
GREM1 gremlin 1, DAN family BMP antagonist
HIST1H2BG histone cluster 1, H2bg
HIST1H4C histone cluster 1, H4c
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HSPA1A heat shock 70kDa protein 1A
IFI6 interferon, alpha-inducible protein 6
KRAS Kirsten rat sarcoma viral oncogene homolog
LEPROT leptin receptor overlapping transcript
LMO3 LIM domain only 3 (rhombotin-like 2)
MFAP5 microfibrillar associated protein 5
MMP1 matrix metallopeptidase 1
OSBPL8 oxysterol binding protein-like 8
PTPRD protein tyrosine phosphatase, receptor type, D
RPL37A ribosomal protein L37a
RPS11 ribosomal protein S11
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SPON1 spondin 1, extracellular matrix protein
SSBP2 single-stranded DNA binding protein 2
TES testin LIM domain protein
TXNIP thioredoxin interacting protein
VIM vimentin

decreased expression

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
C10ORF10 chromosome 10 open reading frame 10
CA12 carbonic anhydrase XII
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CCL2 chemokine (C-C motif) ligand 2
CD24 CD24 molecule
CRISP3 cysteine-rich secretory protein 3
CSTA cystatin A (stefin A)
DKK1 dickkopf WNT signaling pathway inhibitor 1
EMP2 epithelial membrane protein 2
FGG fibrinogen gamma chain
GPI glucose-6-phosphate isomerase
HBB hemoglobin, beta
HES1 hes family bHLH transcription factor 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
KRT14 keratin 14, type I
KYNU kynureninase
LPL lipoprotein lipase
MRPS2 mitochondrial ribosomal protein S2
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NRN1 neuritin 1
PLAC8 placenta-specific 8
PODXL podocalyxin-like
RFTN1 raftlin, lipid raft linker 1
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
S100A2 S100 calcium binding protein A2
S100A7 S100 calcium binding protein A7
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SOX9 SRY (sex determining region Y)-box 9
TBX2 T-box 2
VCAM1 vascular cell adhesion molecule 1
ZBTB18 zinc finger and BTB domain containing 18