BRD-K64890080_BI-2536_SKBR3_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

98 genes differentially expressed following the BRD-K64890080_BI-2536_SKBR3_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRG2 adhesion G protein-coupled receptor G2
AKAP8L A kinase (PRKA) anchor protein 8-like
ALCAM activated leukocyte cell adhesion molecule
AURKA aurora kinase A
CCDC92 coiled-coil domain containing 92
CD52 CD52 molecule
CDC20 cell division cycle 20
CHGB chromogranin B
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
COTL1 coactosin-like F-actin binding protein 1
FAS Fas cell surface death receptor
JUN jun proto-oncogene
MEG3 maternally expressed 3 (non-protein coding)
MID1 midline 1
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NCAM1 neural cell adhesion molecule 1
NEFM neurofilament, medium polypeptide
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NTS neurotensin
PCDH9 protocadherin 9
PLK1 polo-like kinase 1
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PRKACB protein kinase, cAMP-dependent, catalytic, beta
QPCT glutaminyl-peptide cyclotransferase
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SNX11 sorting nexin 11
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
TUBB6 tubulin, beta 6 class V
UBE2S ubiquitin-conjugating enzyme E2S
VIM vimentin

decreased expression

Symbol Name
AIM1 absent in melanoma 1
AQP1 aquaporin 1 (Colton blood group)
AQP3 aquaporin 3 (Gill blood group)
ASPN asporin
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
C10ORF10 chromosome 10 open reading frame 10
C3 complement component 3
CA2 carbonic anhydrase II
CCL2 chemokine (C-C motif) ligand 2
CCNE2 cyclin E2
CD93 CD93 molecule
COL15A1 collagen, type XV, alpha 1
CRABP2 cellular retinoic acid binding protein 2
CRELD2 cysteine-rich with EGF-like domains 2
CTSH cathepsin H
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL14 chemokine (C-X-C motif) ligand 14
DEFB1 defensin, beta 1
EMP1 epithelial membrane protein 1
FKBP11 FK506 binding protein 11, 19 kDa
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GNPDA1 glucosamine-6-phosphate deaminase 1
GRB7 growth factor receptor-bound protein 7
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
IFITM2 interferon induced transmembrane protein 2
IFITM3 interferon induced transmembrane protein 3
ITGB6 integrin, beta 6
ITM2A integral membrane protein 2A
KRT14 keratin 14, type I
KRT17 keratin 17, type I
LAPTM4B lysosomal protein transmembrane 4 beta
LPAR6 lysophosphatidic acid receptor 6
MECOM MDS1 and EVI1 complex locus
MGP matrix Gla protein
MLF1 myeloid leukemia factor 1
MXRA5 matrix-remodelling associated 5
NPY neuropeptide Y
OXA1L oxidase (cytochrome c) assembly 1-like
PI3 peptidase inhibitor 3, skin-derived
PLAC8 placenta-specific 8
PLBD1 phospholipase B domain containing 1
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PROM1 prominin 1
RAB40B RAB40B, member RAS oncogene family
RGCC regulator of cell cycle
RNASET2 ribonuclease T2
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A2 S100 calcium binding protein A2
S100A7 S100 calcium binding protein A7
S100A9 S100 calcium binding protein A9
SOD2 superoxide dismutase 2, mitochondrial
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
STEAP1 six transmembrane epithelial antigen of the prostate 1
TACSTD2 tumor-associated calcium signal transducer 2
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TGFB3 transforming growth factor, beta 3
THBD thrombomodulin
TM4SF1 transmembrane 4 L six family member 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TSPO translocator protein (18kDa)
VWF von Willebrand factor
XBP1 X-box binding protein 1