BRD-K64890080_BI-2536_MDAMB231_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

60 genes differentially expressed following the BRD-K64890080_BI-2536_MDAMB231_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
BEX1 brain expressed, X-linked 1
CNOT4 CCR4-NOT transcription complex, subunit 4
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
GLS glutaminase
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NPR3 natriuretic peptide receptor 3
NR4A2 nuclear receptor subfamily 4, group A, member 2
PAN2 PAN2 poly(A) specific ribonuclease subunit
PECAM1 platelet/endothelial cell adhesion molecule 1
PLIN2 perilipin 2
PLK1 polo-like kinase 1
PRUNE2 prune homolog 2 (Drosophila)
RTCA RNA 3'-terminal phosphate cyclase
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC38A1 solute carrier family 38, member 1
SRGN serglycin
STXBP1 syntaxin binding protein 1

decreased expression

Symbol Name
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AQP3 aquaporin 3 (Gill blood group)
BACE2 beta-site APP-cleaving enzyme 2
C3 complement component 3
CBR3 carbonyl reductase 3
CCNE2 cyclin E2
CLTB clathrin, light chain B
COL15A1 collagen, type XV, alpha 1
CPA3 carboxypeptidase A3 (mast cell)
CXCL13 chemokine (C-X-C motif) ligand 13
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
FAM129A family with sequence similarity 129, member A
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial
HLA-B major histocompatibility complex, class I, B
IFI16 interferon, gamma-inducible protein 16
IGFBP3 insulin-like growth factor binding protein 3
IGL immunoglobulin lambda locus
IL17RB interleukin 17 receptor B
KRT14 keratin 14, type I
KRT17 keratin 17, type I
KRT19 keratin 19, type I
KRT5 keratin 5, type II
KRT6B keratin 6B, type II
MCM3 minichromosome maintenance complex component 3
MMP11 matrix metallopeptidase 11
MPZL2 myelin protein zero-like 2
MXRA5 matrix-remodelling associated 5
PERP PERP, TP53 apoptosis effector
PTN pleiotrophin
RAD23B RAD23 homolog B (S. cerevisiae)
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
S100A9 S100 calcium binding protein A9
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SPARCL1 SPARC-like 1 (hevin)
SPRR1A small proline-rich protein 1A
TRIP6 thyroid hormone receptor interactor 6
WNT5A wingless-type MMTV integration site family, member 5A
YBX3 Y box binding protein 3