BRD-K64890080_BI-2536_MCF7_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

87 genes differentially expressed following the BRD-K64890080_BI-2536_MCF7_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACPP acid phosphatase, prostate
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
ALDOC aldolase C, fructose-bisphosphate
ARG2 arginase 2
ATF3 activating transcription factor 3
CCL5 chemokine (C-C motif) ligand 5
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHEK2 checkpoint kinase 2
DCN decorin
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF5A eukaryotic translation initiation factor 5A
ETV1 ets variant 1
FAM134B family with sequence similarity 134, member B
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GPX3 glutathione peroxidase 3
GSN gelsolin
HAPLN1 hyaluronan and proteoglycan link protein 1
HIST1H1C histone cluster 1, H1c
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-F major histocompatibility complex, class I, F
HLA-G major histocompatibility complex, class I, G
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IDI1 isopentenyl-diphosphate delta isomerase 1
IGFBP5 insulin-like growth factor binding protein 5
KIF2C kinesin family member 2C
LGMN legumain
LUM lumican
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MMP3 matrix metallopeptidase 3
NCAM1 neural cell adhesion molecule 1
NEBL nebulette
NEFH neurofilament, heavy polypeptide
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
PCDH9 protocadherin 9
PCNA proliferating cell nuclear antigen
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
RPS4Y1 ribosomal protein S4, Y-linked 1
SATB1 SATB homeobox 1
SDC2 syndecan 2
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SIK1 salt-inducible kinase 1
SMTN smoothelin
SOX9 SRY (sex determining region Y)-box 9
SPRR3 small proline-rich protein 3
SRPX sushi-repeat containing protein, X-linked
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMSB15A thymosin beta 15a
TNC tenascin C
TUBB2A tubulin, beta 2A class IIa

decreased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
AHR aryl hydrocarbon receptor
ATF1 activating transcription factor 1
C2CD2 C2 calcium-dependent domain containing 2
DKK1 dickkopf WNT signaling pathway inhibitor 1
ESR1 estrogen receptor 1
FCGBP Fc fragment of IgG binding protein
KAT6B K(lysine) acetyltransferase 6B
MECOM MDS1 and EVI1 complex locus
NRIP1 nuclear receptor interacting protein 1
PODXL podocalyxin-like
RBP1 retinol binding protein 1, cellular
RIN2 Ras and Rab interactor 2
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SCGB2A2 secretoglobin, family 2A, member 2
SNRPE small nuclear ribonucleoprotein polypeptide E
SPAG4 sperm associated antigen 4
STC2 stanniocalcin 2
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNS3 tensin 3
XIST X inactive specific transcript (non-protein coding)
ZNF512B zinc finger protein 512B
ZNF586 zinc finger protein 586