BRD-K64890080_BI-2536_MCF10A_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

113 genes differentially expressed following the BRD-K64890080_BI-2536_MCF10A_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ASMTL acetylserotonin O-methyltransferase-like
BRD2 bromodomain containing 2
C14ORF132 chromosome 14 open reading frame 132
C9ORF16 chromosome 9 open reading frame 16
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CADM1 cell adhesion molecule 1
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CKB creatine kinase, brain
CLDN10 claudin 10
CPE carboxypeptidase E
DLX2 distal-less homeobox 2
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DPYSL3 dihydropyrimidinase-like 3
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EGR1 early growth response 1
EGR3 early growth response 3
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
FGG fibrinogen gamma chain
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FZD7 frizzled class receptor 7
GADD45B growth arrest and DNA-damage-inducible, beta
GALC galactosylceramidase
GATA6 GATA binding protein 6
GPX3 glutathione peroxidase 3
GSTM3 glutathione S-transferase mu 3 (brain)
H2BFS H2B histone family, member S (pseudogene)
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IER3 immediate early response 3
IER5 immediate early response 5
IFI6 interferon, alpha-inducible protein 6
INSIG1 insulin induced gene 1
JUNB jun B proto-oncogene
KIF2C kinesin family member 2C
LRRC16A leucine rich repeat containing 16A
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MLF1 myeloid leukemia factor 1
NEBL nebulette
NMU neuromedin U
NR4A2 nuclear receptor subfamily 4, group A, member 2
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PRSS2 protease, serine, 2 (trypsin 2)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RPL37A ribosomal protein L37a
RPS4Y1 ribosomal protein S4, Y-linked 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SYNGR3 synaptogyrin 3
TFF3 trefoil factor 3 (intestinal)
TMEM2 transmembrane protein 2
WSB1 WD repeat and SOCS box containing 1
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
ACSL5 acyl-CoA synthetase long-chain family member 5
ADAM12 ADAM metallopeptidase domain 12
ADRB2 adrenoceptor beta 2, surface
AOX1 aldehyde oxidase 1
AQP3 aquaporin 3 (Gill blood group)
ATF1 activating transcription factor 1
C1ORF106 chromosome 1 open reading frame 106
CASP1 caspase 1, apoptosis-related cysteine peptidase
CDCA4 cell division cycle associated 4
CHD7 chromodomain helicase DNA binding protein 7
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CLCA2 chloride channel accessory 2
CPA3 carboxypeptidase A3 (mast cell)
CSTA cystatin A (stefin A)
CXCL14 chemokine (C-X-C motif) ligand 14
DKK1 dickkopf WNT signaling pathway inhibitor 1
DPP4 dipeptidyl-peptidase 4
EGFR epidermal growth factor receptor
EVI2A ecotropic viral integration site 2A
EVI2B ecotropic viral integration site 2B
FAS Fas cell surface death receptor
HMGA2 high mobility group AT-hook 2
HOPX HOP homeobox
HOXA10 homeobox A10
IL1B interleukin 1, beta
JADE2 jade family PHD finger 2
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCNK1 potassium channel, two pore domain subfamily K, member 1
KIAA0485 uncharacterized LOC57235
KIF14 kinesin family member 14
KLHL9 kelch-like family member 9
KRT14 keratin 14, type I
KRT17 keratin 17, type I
KRT5 keratin 5, type II
LTF lactotransferrin
MICALL1 MICAL-like 1
MME membrane metallo-endopeptidase
MYC v-myc avian myelocytomatosis viral oncogene homolog
NUP85 nucleoporin 85kDa
PARP2 poly (ADP-ribose) polymerase 2
PLN phospholamban
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
S100A2 S100 calcium binding protein A2
S100A8 S100 calcium binding protein A8
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SPG20 spastic paraplegia 20 (Troyer syndrome)
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SPP1 secreted phosphoprotein 1
SPRED2 sprouty-related, EVH1 domain containing 2
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TACSTD2 tumor-associated calcium signal transducer 2
TNNI2 troponin I type 2 (skeletal, fast)
TRD T cell receptor delta locus