BRD-K64890080_BI-2536_HS578T_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

102 genes differentially expressed following the BRD-K64890080_BI-2536_HS578T_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AK1 adenylate kinase 1
ATF3 activating transcription factor 3
BTG2 BTG family, member 2
C8ORF4 chromosome 8 open reading frame 4
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CD9 CD9 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CLDN10 claudin 10
CTSK cathepsin K
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP2 dual specificity phosphatase 2
DUSP5 dual specificity phosphatase 5
FBLN1 fibulin 1
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GADD45B growth arrest and DNA-damage-inducible, beta
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H3H histone cluster 1, H3h
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IER5 immediate early response 5
KLF4 Kruppel-like factor 4 (gut)
LOC100505650 uncharacterized LOC100505650
MAN1A1 mannosidase, alpha, class 1A, member 1
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
NBL1 neuroblastoma 1, DAN family BMP antagonist
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
RGS2 regulator of G-protein signaling 2
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SIK1 salt-inducible kinase 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SPON1 spondin 1, extracellular matrix protein
STAP2 signal transducing adaptor family member 2
TFRC transferrin receptor
ZFP36 ZFP36 ring finger protein
ZNF331 zinc finger protein 331

decreased expression

Symbol Name
ACSL1 acyl-CoA synthetase long-chain family member 1
ADGRG2 adhesion G protein-coupled receptor G2
ADIPOQ adiponectin, C1Q and collagen domain containing
ALCAM activated leukocyte cell adhesion molecule
AMOTL2 angiomotin like 2
ANXA1 annexin A1
APOD apolipoprotein D
ARID5B AT rich interactive domain 5B (MRF1-like)
ATF1 activating transcription factor 1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
AZU1 azurocidin 1
BEX1 brain expressed, X-linked 1
CCL2 chemokine (C-C motif) ligand 2
CFD complement factor D (adipsin)
CPD carboxypeptidase D
CSTA cystatin A (stefin A)
CTSG cathepsin G
DKK1 dickkopf WNT signaling pathway inhibitor 1
ELANE elastase, neutrophil expressed
EREG epiregulin
F5 coagulation factor V (proaccelerin, labile factor)
FNDC3B fibronectin type III domain containing 3B
FXYD5 FXYD domain containing ion transport regulator 5
HOXA10 homeobox A10
HOXB6 homeobox B6
IRS2 insulin receptor substrate 2
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
KRT18 keratin 18, type I
LYPLA1 lysophospholipase I
MAP1B microtubule-associated protein 1B
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MNDA myeloid cell nuclear differentiation antigen
MPO myeloperoxidase
MRPS18B mitochondrial ribosomal protein S18B
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
MX2 MX dynamin-like GTPase 2
NPTX2 neuronal pentraxin II
PLA2G16 phospholipase A2, group XVI
PLAC8 placenta-specific 8
PRPF4 pre-mRNA processing factor 4
PUF60 poly-U binding splicing factor 60KDa
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RNASE3 ribonuclease, RNase A family, 3
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
S100P S100 calcium binding protein P
SEC61G Sec61 gamma subunit
SELL selectin L
SNRPE small nuclear ribonucleoprotein polypeptide E
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SPRED2 sprouty-related, EVH1 domain containing 2
SRGN serglycin
SUB1 SUB1 homolog (S. cerevisiae)
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TARP TCR gamma alternate reading frame protein
TFPI2 tissue factor pathway inhibitor 2
TLR4 toll-like receptor 4
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNS3 tensin 3