BRD-K64890080_BI-2536_BT20_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

59 genes differentially expressed following the BRD-K64890080_BI-2536_BT20_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
CAPG capping protein (actin filament), gelsolin-like
CDH13 cadherin 13
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CETN2 centrin, EF-hand protein, 2
CHRDL1 chordin-like 1
CTSH cathepsin H
EDNRA endothelin receptor type A
EFNB2 ephrin-B2
FN1 fibronectin 1
HIST1H2AC histone cluster 1, H2ac
HIST1H2BK histone cluster 1, H2bk
HIST2H2BE histone cluster 2, H2be
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IL17RB interleukin 17 receptor B
IRF8 interferon regulatory factor 8
JUN jun proto-oncogene
KIAA0226L KIAA0226-like
LAMP5 lysosomal-associated membrane protein family, member 5
MAN1A1 mannosidase, alpha, class 1A, member 1
NEBL nebulette
NOTCH1 notch 1
NRIP3 nuclear receptor interacting protein 3
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PCP4 Purkinje cell protein 4
PRUNE2 prune homolog 2 (Drosophila)
SDC2 syndecan 2
SPINT2 serine peptidase inhibitor, Kunitz type, 2
TSC22D1 TSC22 domain family, member 1
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
ABHD4 abhydrolase domain containing 4
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CLC Charcot-Leyden crystal galectin
COCH cochlin
DUSP4 dual specificity phosphatase 4
FAM129A family with sequence similarity 129, member A
FBLN1 fibulin 1
FSCN1 fascin actin-bundling protein 1
GBP2 guanylate binding protein 2, interferon-inducible
HES1 hes family bHLH transcription factor 1
HMOX1 heme oxygenase 1
KRT13 keratin 13, type I
KRT15 keratin 15, type I
LPAR1 lysophosphatidic acid receptor 1
LY6E lymphocyte antigen 6 complex, locus E
MFAP4 microfibrillar-associated protein 4
NUP50 nucleoporin 50kDa
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
RTN2 reticulon 2
SLAMF7 SLAM family member 7
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SYNJ2 synaptojanin 2
TFPI2 tissue factor pathway inhibitor 2
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
UBE2C ubiquitin-conjugating enzyme E2C