BRD-K64890080_BI-2536_A549_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

118 genes differentially expressed following the BRD-K64890080_BI-2536_A549_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
AURKA aurora kinase A
CCNA1 cyclin A1
CCNB2 cyclin B2
CCNF cyclin F
FOSL1 FOS-like antigen 1
GAL galanin/GMAP prepropeptide
HIST1H2BD histone cluster 1, H2bd
HIST1H2BG histone cluster 1, H2bg
JMJD6 jumonji domain containing 6
KLF5 Kruppel-like factor 5 (intestinal)
PHACTR2 phosphatase and actin regulator 2
PHLDA1 pleckstrin homology-like domain, family A, member 1
QKI QKI, KH domain containing, RNA binding
S100A2 S100 calcium binding protein A2
TBX2 T-box 2
TCL1A T-cell leukemia/lymphoma 1A
TGFA transforming growth factor, alpha
TUBB6 tubulin, beta 6 class V
ZCCHC14 zinc finger, CCHC domain containing 14
ZNF331 zinc finger protein 331
ZNF586 zinc finger protein 586
ZNF91 zinc finger protein 91
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
AGR2 anterior gradient 2
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALB albumin
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ANG angiogenin, ribonuclease, RNase A family, 5
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANXA4 annexin A4
APOA2 apolipoprotein A-II
APOH apolipoprotein H (beta-2-glycoprotein I)
BCHE butyrylcholinesterase
BIN1 bridging integrator 1
C3ORF14 chromosome 3 open reading frame 14
C4BPA complement component 4 binding protein, alpha
C8ORF4 chromosome 8 open reading frame 4
CCNE2 cyclin E2
CD99 CD99 molecule
CDK1 cyclin-dependent kinase 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHRDL1 chordin-like 1
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
COL6A3 collagen, type VI, alpha 3
CP ceruloplasmin (ferroxidase)
CRIP1 cysteine-rich protein 1 (intestinal)
CXCL10 chemokine (C-X-C motif) ligand 10
DPYD dihydropyrimidine dehydrogenase
ENO1 enolase 1, (alpha)
FAM129A family with sequence similarity 129, member A
FCGBP Fc fragment of IgG binding protein
FGA fibrinogen alpha chain
FGB fibrinogen beta chain
FGG fibrinogen gamma chain
FGL1 fibrinogen-like 1
FMO5 flavin containing monooxygenase 5
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GPX3 glutathione peroxidase 3
HES1 hes family bHLH transcription factor 1
HLF hepatic leukemia factor
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IFI16 interferon, gamma-inducible protein 16
IFI44L interferon-induced protein 44-like
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
ISG15 ISG15 ubiquitin-like modifier
ITM2A integral membrane protein 2A
LACTB2 lactamase, beta 2
LMO3 LIM domain only 3 (rhombotin-like 2)
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAOB monoamine oxidase B
MDK midkine (neurite growth-promoting factor 2)
MLPH melanophilin
MRPS2 mitochondrial ribosomal protein S2
MYBPC1 myosin binding protein C, slow type
NAMPT nicotinamide phosphoribosyltransferase
NKX2-1 NK2 homeobox 1
NOVA1 neuro-oncological ventral antigen 1
NREP neuronal regeneration related protein
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OLFML3 olfactomedin-like 3
PAIP1 poly(A) binding protein interacting protein 1
PCSK6 proprotein convertase subtilisin/kexin type 6
PLAC8 placenta-specific 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTN pleiotrophin
RAP1GAP RAP1 GTPase activating protein
REEP1 receptor accessory protein 1
RHOBTB1 Rho-related BTB domain containing 1
RNASE4 ribonuclease, RNase A family, 4
RRAS2 related RAS viral (r-ras) oncogene homolog 2
S100P S100 calcium binding protein P
SCGB1D2 secretoglobin, family 1D, member 2
SFTPA2 surfactant protein A2
SMAD1 SMAD family member 1
SNAP25 synaptosomal-associated protein, 25kDa
SORD sorbitol dehydrogenase
STEAP1 six transmembrane epithelial antigen of the prostate 1
SYNM synemin, intermediate filament protein
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TM4SF4 transmembrane 4 L six family member 4
TMC5 transmembrane channel-like 5
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TSPAN8 tetraspanin 8
UBE2C ubiquitin-conjugating enzyme E2C
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
VSIG4 V-set and immunoglobulin domain containing 4