BRD-K64857848_XMD-885_HCC515_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

78 genes differentially expressed following the BRD-K64857848_XMD-885_HCC515_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CD99 CD99 molecule
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
CPNE3 copine III
CSRP2 cysteine and glycine-rich protein 2
EFNB2 ephrin-B2
ELF1 E74-like factor 1 (ets domain transcription factor)
ENC1 ectodermal-neural cortex 1 (with BTB domain)
GAS7 growth arrest-specific 7
H1F0 H1 histone family, member 0
H2BFS H2B histone family, member S (pseudogene)
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HIST1H1C histone cluster 1, H1c
HIST1H2BK histone cluster 1, H2bk
HIST3H2A histone cluster 3, H2a
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
IQGAP2 IQ motif containing GTPase activating protein 2
MCOLN1 mucolipin 1
NDUFAF3 NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
PECAM1 platelet/endothelial cell adhesion molecule 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PRKCQ protein kinase C, theta
QPCT glutaminyl-peptide cyclotransferase
RAB15 RAB15, member RAS oncogene family
RRAGD Ras-related GTP binding D
SLC16A6 solute carrier family 16, member 6
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SOX9 SRY (sex determining region Y)-box 9
SPARCL1 SPARC-like 1 (hevin)
STAP2 signal transducing adaptor family member 2
STAT5B signal transducer and activator of transcription 5B
STXBP6 syntaxin binding protein 6 (amisyn)
TIMP3 TIMP metallopeptidase inhibitor 3
TMSB15A thymosin beta 15a
TTC3 tetratricopeptide repeat domain 3
VWF von Willebrand factor

decreased expression

Symbol Name
ADGRG6 adhesion G protein-coupled receptor G6
AKAP7 A kinase (PRKA) anchor protein 7
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALCAM activated leukocyte cell adhesion molecule
CALD1 caldesmon 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL8 chemokine (C-X-C motif) ligand 8
DHCR24 24-dehydrocholesterol reductase
DPYSL3 dihydropyrimidinase-like 3
DST dystonin
DUSP5 dual specificity phosphatase 5
EXT1 exostosin glycosyltransferase 1
FOSL1 FOS-like antigen 1
GCH1 GTP cyclohydrolase 1
GOLGA8A golgin A8 family, member A
GOLGA8B golgin A8 family, member B
HBB hemoglobin, beta
IFI16 interferon, gamma-inducible protein 16
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGHM immunoglobulin heavy constant mu
KIAA0101 KIAA0101
KRT19 keratin 19, type I
LAPTM4B lysosomal protein transmembrane 4 beta
LY96 lymphocyte antigen 96
MARCKS myristoylated alanine-rich protein kinase C substrate
MELK maternal embryonic leucine zipper kinase
MFAP5 microfibrillar associated protein 5
MT1E metallothionein 1E
NNMT nicotinamide N-methyltransferase
RGS2 regulator of G-protein signaling 2
RRM2 ribonucleotide reductase M2
SFRP4 secreted frizzled-related protein 4
SOX11 SRY (sex determining region Y)-box 11
SRGN serglycin
TM4SF1 transmembrane 4 L six family member 1
TNC tenascin C
TUSC3 tumor suppressor candidate 3
VGLL4 vestigial-like family member 4
ZWINT ZW10 interacting kinetochore protein