BRD-K64857848_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

95 genes differentially expressed following the BRD-K64857848_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACOT7 acyl-CoA thioesterase 7
ALDOC aldolase C, fructose-bisphosphate
ASMTL acetylserotonin O-methyltransferase-like
BAG3 BCL2-associated athanogene 3
CA2 carbonic anhydrase II
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CCDC92 coiled-coil domain containing 92
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CIRBP cold inducible RNA binding protein
COL11A1 collagen, type XI, alpha 1
COL3A1 collagen, type III, alpha 1
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
DCN decorin
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DUSP10 dual specificity phosphatase 10
DUSP14 dual specificity phosphatase 14
ETV1 ets variant 1
GLRX glutaredoxin (thioltransferase)
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BE histone cluster 1, H2be
HIST1H2BF histone cluster 1, H2bf
HIST1H2BH histone cluster 1, H2bh
HIST1H2BK histone cluster 1, H2bk
HIST1H3H histone cluster 1, H3h
HIST3H2A histone cluster 3, H2a
HSPA1A heat shock 70kDa protein 1A
IDI1 isopentenyl-diphosphate delta isomerase 1
INSIG1 insulin induced gene 1
IRF7 interferon regulatory factor 7
KLHDC2 kelch domain containing 2
KRT5 keratin 5, type II
LAMP2 lysosomal-associated membrane protein 2
MSRB2 methionine sulfoxide reductase B2
MYO1B myosin IB
NEB nebulin
NOTCH1 notch 1
PPAP2B phosphatidic acid phosphatase type 2B
SFN stratifin
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
TMEM2 transmembrane protein 2
TXNIP thioredoxin interacting protein
UBE2A ubiquitin-conjugating enzyme E2A
VNN1 vanin 1
WIPI1 WD repeat domain, phosphoinositide interacting 1

decreased expression

Symbol Name
ABLIM1 actin binding LIM protein 1
ADORA2B adenosine A2b receptor
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
AREG amphiregulin
BMP4 bone morphogenetic protein 4
CD200 CD200 molecule
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CFI complement factor I
CIAPIN1 cytokine induced apoptosis inhibitor 1
DPH2 DPH2 homolog (S. cerevisiae)
EIF4B eukaryotic translation initiation factor 4B
EMG1 EMG1 N1-specific pseudouridine methyltransferase
EREG epiregulin
ESR1 estrogen receptor 1
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FOSL1 FOS-like antigen 1
GPR171 G protein-coupled receptor 171
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFRD2 interferon-related developmental regulator 2
MAPK13 mitogen-activated protein kinase 13
MBNL2 muscleblind-like splicing regulator 2
MFSD10 major facilitator superfamily domain containing 10
MPPED2 metallophosphoesterase domain containing 2
MRPL3 mitochondrial ribosomal protein L3
MYC v-myc avian myelocytomatosis viral oncogene homolog
NOP16 NOP16 nucleolar protein
NTS neurotensin
PEG3 paternally expressed 3
PLBD1 phospholipase B domain containing 1
PPARG peroxisome proliferator-activated receptor gamma
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTX3 pentraxin 3, long
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SCD5 stearoyl-CoA desaturase 5
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SPG20 spastic paraplegia 20 (Troyer syndrome)
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SYNGR1 synaptogyrin 1
TCERG1 transcription elongation regulator 1
TFPI2 tissue factor pathway inhibitor 2
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TM4SF1 transmembrane 4 L six family member 1
TSEN2 TSEN2 tRNA splicing endonuclease subunit
TSPAN8 tetraspanin 8
ZNF91 zinc finger protein 91