BRD-K64800655_PHA-793887_SKBR3_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

111 genes differentially expressed following the BRD-K64800655_PHA-793887_SKBR3_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ANOS1 anosmin 1
ANXA5 annexin A5
AREG amphiregulin
CLIC5 chloride intracellular channel 5
COL15A1 collagen, type XV, alpha 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EGFL6 EGF-like-domain, multiple 6
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EMP1 epithelial membrane protein 1
EPB41L3 erythrocyte membrane protein band 4.1-like 3
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GALC galactosylceramidase
GSTT1 glutathione S-transferase theta 1
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
KDM5D lysine (K)-specific demethylase 5D
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KIAA0226L KIAA0226-like
KIF5B kinesin family member 5B
LAMP3 lysosomal-associated membrane protein 3
LPXN leupaxin
LRRC16A leucine rich repeat containing 16A
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MDFIC MyoD family inhibitor domain containing
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MEIS1 Meis homeobox 1
MXRA5 matrix-remodelling associated 5
NARS asparaginyl-tRNA synthetase
NTS neurotensin
OSBPL10 oxysterol binding protein-like 10
PLAT plasminogen activator, tissue
PRAME preferentially expressed antigen in melanoma
RBP1 retinol binding protein 1, cellular
RNASE6 ribonuclease, RNase A family, k6
RNH1 ribonuclease/angiogenin inhibitor 1
RPL39L ribosomal protein L39-like
RPS4Y1 ribosomal protein S4, Y-linked 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SMAD2 SMAD family member 2
SPON1 spondin 1, extracellular matrix protein
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit
TES testin LIM domain protein
TFRC transferrin receptor
TGFA transforming growth factor, alpha
THBS4 thrombospondin 4
TIMP3 TIMP metallopeptidase inhibitor 3
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
VIM vimentin

decreased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
ARG1 arginase 1
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
AURKA aurora kinase A
AZGP1 alpha-2-glycoprotein 1, zinc-binding
C10ORF10 chromosome 10 open reading frame 10
CCL2 chemokine (C-C motif) ligand 2
CCNA2 cyclin A2
CCNE2 cyclin E2
CCNF cyclin F
CD24 CD24 molecule
CD59 CD59 molecule, complement regulatory protein
CDC20 cell division cycle 20
CDK7 cyclin-dependent kinase 7
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CKS2 CDC28 protein kinase regulatory subunit 2
CLU clusterin
CRISP3 cysteine-rich secretory protein 3
DDIT4 DNA-damage-inducible transcript 4
DUSP1 dual specificity phosphatase 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGFR epidermal growth factor receptor
EIF5 eukaryotic translation initiation factor 5
EXT1 exostosin glycosyltransferase 1
FDFT1 farnesyl-diphosphate farnesyltransferase 1
HES1 hes family bHLH transcription factor 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFBP6 insulin-like growth factor binding protein 6
IVNS1ABP influenza virus NS1A binding protein
KANK1 KN motif and ankyrin repeat domains 1
KIAA0355 KIAA0355
KIF14 kinesin family member 14
KLHL9 kelch-like family member 9
KLK5 kallikrein-related peptidase 5
LTF lactotransferrin
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NPY neuropeptide Y
NUP62 nucleoporin 62kDa
ORM1 orosomucoid 1
RAD9A RAD9 homolog A (S. pombe)
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RCAN1 regulator of calcineurin 1
RGS4 regulator of G-protein signaling 4
S100A12 S100 calcium binding protein A12
SAV1 salvador family WW domain containing protein 1
SLPI secretory leukocyte peptidase inhibitor
STC2 stanniocalcin 2
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TSC22D3 TSC22 domain family, member 3
TXNIP thioredoxin interacting protein
XBP1 X-box binding protein 1
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)
ZNF22 zinc finger protein 22